Fatigue, depression, and pain in multiple sclerosis: how neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms

H Heitmann, TFM Andlauer, T Korn… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Fatigue, depression, and pain affect the majority of multiple sclerosis (MS) patients, which
causes a substantial burden to patients and society. The pathophysiology of these symptoms …

Prefrontal gamma oscillations reflect ongoing pain intensity in chronic back pain patients

…, S Ta Dinh, L Tiemann, H Heitmann… - Human brain …, 2019 - Wiley Online Library
Chronic pain is a major health care issue characterized by ongoing pain and a variety of
sensory, cognitive, and affective abnormalities. The neural basis of chronic pain is still not …

Brain dysfunction in chronic pain patients assessed by resting-state electroencephalography

ST Dinh, MM Nickel, L Tiemann, ES May, H Heitmann… - Pain, 2019 - journals.lww.com
Chronic pain is a common and severely disabling disease whose treatment is often
unsatisfactory. Insights into the brain mechanisms of chronic pain promise to advance the …

Prevalence of neuropathic pain in early multiple sclerosis

H Heitmann, V Biberacher, L Tiemann… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Pain is considered a frequent symptom in multiple sclerosis. Neuropathic pain
is the type of pain most closely related to the pathology of multiple sclerosis and its …

[HTML][HTML] Dopamine precursor depletion influences pain affect rather than pain sensation

L Tiemann, H Heitmann, E Schulz, J Baumkötter… - PLoS …, 2014 - journals.plos.org
Pain is a multidimensional experience, which includes sensory, cognitive, and affective
aspects. Converging lines of evidence indicate that dopaminergic neurotransmission plays an …

[HTML][HTML] Resting-state EEG and MEG biomarkers of pathological fatigue–A transdiagnostic systematic review

H Heitmann, PT Zebhauser, VD Hohn… - NeuroImage: Clinical, 2023 - Elsevier
Fatigue is a highly prevalent and disabling symptom of many disorders and syndromes,
resulting from different pathomechanisms. However, whether and how different mechanisms …

[HTML][HTML] Dynamics of brain function in patients with chronic pain assessed by microstate analysis of resting-state electroencephalography

ES May, CG Ávila, ST Dinh, H Heitmann, VD Hohn… - Pain, 2021 - journals.lww.com
Chronic pain is a highly prevalent and severely disabling disease that is associated with
substantial changes of brain function. Such changes have mostly been observed when …

[HTML][HTML] Effectiveness of non-bedside teaching during the COVID-19 pandemic: a quasi-experimental study

H Heitmann, P Wagner, E Fischer, M Gartmeier… - BMC Medical …, 2022 - Springer
Background The COVID-19 pandemic poses a huge challenge for clinical teaching due to
contact restrictions and social distancing. Medical teachers have to balance potential risks …

Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study

H Heitmann, B Haller, L Tiemann, M Mühlau… - Pain, 2020 - journals.lww.com
Pain is frequent in multiple sclerosis (MS) and includes different types, with neuropathic
pain (NP) being most closely related to MS pathology. However, prevalence estimates vary …

[HTML][HTML] Modulating brain rhythms of pain using transcranial alternating current stimulation (tACS)-a sham-controlled study in healthy human participants

…, MM Nickel, L Tiemann, CG Ávila, H Heitmann… - The Journal of …, 2021 - Elsevier
Chronic pain is a major health care problem. A better mechanistic understanding and new
treatment approaches are urgently needed. In the brain, pain has been associated with neural …