User profiles for Helmut Heinsen
Helmut Heinsensenior professor, Julius-Maximilians-Universit Würzbutg; FMUSP Verified email at mail.uni-wuerzburg.de Cited by 12425 |
Minicolumnar abnormalities in autism
…, AE Switala, H van Engeland, H Heinsen… - Acta …, 2006 - Springer
Autism is characterized by qualitative abnormalities in behavior and higher order cognitive
functions. Minicolumnar irregularities observed in autism provide a neurologically sound …
functions. Minicolumnar irregularities observed in autism provide a neurologically sound …
Molecular characterization of selectively vulnerable neurons in Alzheimer's disease
Alzheimer’s disease (AD) is characterized by the selective vulnerability of specific neuronal
populations, the molecular signatures of which are largely unknown. To identify and …
populations, the molecular signatures of which are largely unknown. To identify and …
The brainstem pathologies of Parkinson's disease and dementia with Lewy bodies
Parkinson's disease ( PD ) and dementia with L ewy bodies ( DLB ) are among the human
synucleinopathies, which show alpha‐synuclein immunoreactive neuronal and/or glial …
synucleinopathies, which show alpha‐synuclein immunoreactive neuronal and/or glial …
Neurons in the fusiform gyrus are fewer and smaller in autism
…, P von Cappeln, HWM Steinbusch, H Korr, H Heinsen… - Brain, 2008 - academic.oup.com
Abnormalities in face perception are a core feature of social disabilities in autism. Recent
functional magnetic resonance imaging studies showed that patients with autism could perform …
functional magnetic resonance imaging studies showed that patients with autism could perform …
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: a stereological study in human postmortem brains with potential …
…, W Jacob Filho, U Rueb, J Neuhaus, H Heinsen… - Alzheimer's & …, 2017 - Elsevier
Introduction Alzheimer's disease (AD) progression follows a specific spreading pattern,
emphasizing the need to characterize those brain areas that degenerate first. The brainstem's …
emphasizing the need to characterize those brain areas that degenerate first. The brainstem's …
Atrophy of the cholinergic basal forebrain over the adult age range and in early stages of Alzheimer's disease
BACKGROUND: The basal forebrain cholinergic system (BFCS) is known to undergo
moderate neurodegenerative changes during normal aging as well as severe atrophy in …
moderate neurodegenerative changes during normal aging as well as severe atrophy in …
Measurement of basal forebrain atrophy in Alzheimer's disease using MRI
Alzheimer's disease is characterized by the degeneration and loss of cholinergic neurones
in the nucleus basalis Meynert, located within the substantia innominata at the ventral …
in the nucleus basalis Meynert, located within the substantia innominata at the ventral …
Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases
Pathological alterations to the locus coeruleus, the major source of noradrenaline in the
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …
brain, are histologically evident in early stages of neurodegenerative diseases. Novel MRI …
Volume, neuron density and total neuron number in five subcortical regions in schizophrenia
Several studies have pointed to alterations in mean volumes, neuron densities and total neuron
numbers in the caudate nucleus (CN), putamen, nucleus accumbens (NA), mediodorsal …
numbers in the caudate nucleus (CN), putamen, nucleus accumbens (NA), mediodorsal …
Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study
Histopathological studies in Alzheimer's disease (AD) suggest severe and region-specific
neurodegeneration of the basal forebrain cholinergic system (BFCS). Here, we studied the …
neurodegeneration of the basal forebrain cholinergic system (BFCS). Here, we studied the …