Chronic stress: implications for neuronal morphology, function and neurogenesis
In normal life, organisms are repeatedly exposed to brief periods of stress, most of which
can be controlled and adequately dealt with. The presently available data indicate that such …
can be controlled and adequately dealt with. The presently available data indicate that such …
Stress hormones and AMPA receptor trafficking in synaptic plasticity and memory
HJ Krugers, CC Hoogenraad, L Groc - Nature Reviews Neuroscience, 2010 - nature.com
The acquisition and consolidation of memories of stressful events is modulated by
glucocorticoids, a type of corticosteroid hormone that is released in high levels from the adrenal …
glucocorticoids, a type of corticosteroid hormone that is released in high levels from the adrenal …
Corticosteroid effects on cellular physiology of limbic cells
After stress, circulating levels of stress hormones such as corticosterone are markedly increased.
This will have an impact on the neurophysiology of limbic neurons that highly express …
This will have an impact on the neurophysiology of limbic neurons that highly express …
[HTML][HTML] Corticosterone alters AMPAR mobility and facilitates bidirectional synaptic plasticity
…, M Joëls, CC Hoogenraad, HJ Krugers - PLOS …, 2009 - journals.plos.org
Background The stress hormone corticosterone has the ability both to enhance and suppress
synaptic plasticity and learning and memory processes. However, until today there is very …
synaptic plasticity and learning and memory processes. However, until today there is very …
[HTML][HTML] Chronic stress effects on hippocampal structure and synaptic function: relevance for depression and normalization by anti-glucocorticoid treatment
HJ Krugers, PJ Lucassen, H Karst… - Frontiers in synaptic …, 2010 - frontiersin.org
Exposure of an organism to environmental challenges activates two hormonal systems that
help the organism to adapt. As part of this adaptational process, brain processes are …
help the organism to adapt. As part of this adaptational process, brain processes are …
[HTML][HTML] Early life adversity and adult social behavior: focus on arginine vasopressin and oxytocin as potential mediators
…, V Gazzola, PJ Lucassen, HJ Krugers - Frontiers in behavioral …, 2019 - frontiersin.org
Exposure to stress during the early postnatal period (ie, early life stress, ES) can impact brain
physiology and modify individual variability in adult social behavior. Arginine vasopressin (…
physiology and modify individual variability in adult social behavior. Arginine vasopressin (…
Transient prepubertal mifepristone treatment normalizes deficits in contextual memory and neuronal activity of adult male rats exposed to maternal deprivation
…, A Tsouli, S Trinh, M Arp, HJ Krugers… - ENeuro, 2017 - eneuro.org
Early life adversity is a well-known risk factor for behavioral dysfunction later in life, including
the formation of contextual memory; it is also (transiently) accompanied by hyperactivity of …
the formation of contextual memory; it is also (transiently) accompanied by hyperactivity of …
[HTML][HTML] Effects of mineralocorticoid receptor overexpression on anxiety and memory after early life stress in female mice
…, AP Harris, JR Seckl, HJ Krugers… - Frontiers in behavioral …, 2016 - frontiersin.org
Early-life stress (ELS) is a risk factor for the development of psychopathology, particularly in
women. Human studies have shown that certain haplotypes of NR3C2, encoding the …
women. Human studies have shown that certain haplotypes of NR3C2, encoding the …
Stress and steroid regulation of synaptic transmission: from physiology to pathophysiology
N Maggio, HJ Krugers, M Segal - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Upon exposure to stressful experiences, steroid hormones, neurotransmitters, and
neuromodulators are released which modulate specific processes in the brain. While the release of …
neuromodulators are released which modulate specific processes in the brain. While the release of …
[HTML][HTML] Hormonal regulation of AMPA receptor trafficking and memory formation
HJ Krugers, C Hoogenraad - Frontiers in synaptic neuroscience, 2009 - frontiersin.org
Humans and rodents retain memories for stressful events very well. The facilitated retention
of these memories is normally very useful. However, in susceptible individuals a variety of …
of these memories is normally very useful. However, in susceptible individuals a variety of …