Depression is a devastating illness with a lifetime prevalence of up to 20%. The
neurotransmitter serotonin or 5-hydroxytryptamine (5-HT) is involved in the pathophysiology of …

Current antidepressants are clinically effective only after several weeks of administration. Here,
we show that serotonin 4 (5-HT 4 ) agonists reduce immobility in the forced swimming test…

In vivo microdialysis and single-cell extracellular recordings were used to assess the
involvement of serotonin 2A (5-HT 2A) and serotonin 2C/2B (5-HT 2C/2B) receptors in the effects …

Current antidepressant treatments are inadequate for many individuals, and when they are
effective, they require several weeks of administration before a therapeutic effect can be …

This study investigated, using in vivo microdialysis in the striatum of freely moving rats, the
role of striatal serotonin 2A (5‐HT 2A ) and 5‐HT 2C receptor subtypes in the modulation of …

BACKGROUND: We recently identified a facilitory control exerted by serotonin 4 (5-HT 4 )
receptors on the in vivo firing activity of dorsal raphé nucleus (DRN) serotonergic (5-HT) …

Background There is now a wealth of evidence showing that work is a major determinant of
physical and mental health. Recent studies have suggested increased rates of depression in …

Using first-principles molecular dynamics simulations, we have determined the threshold
displacement energies and the associated created defects in cubic silicon carbide. We found …

We investigated, using single‐unit recordings in chloral hydrate‐anaesthetized rats, the role
of serotonin 4 (5‐HT 4 ) receptors in the control of dorsal raphé nucleus (DRN) 5‐HT neuron …

Decreased serotonin (5‐HT) transmission is thought to underlie several mental diseases,
including depression and feeding disorders. However, whether deficits in genes encoding G …