Objective To demonstrate the safety and effectiveness of responsive stimulation at the seizure
focus as an adjunctive therapy to reduce the frequency of seizures in adults with medically …

Neocortical seizures are often poorly localized, explosive and widespread at onset, making
them poorly amenable to epilepsy surgery in the absence of associated focal brain lesions. …

Neuronal oscillations span a wide range of spatial and temporal scales that extend beyond
traditional clinical EEG. Recent research suggests that high-frequency oscillations (HFO), in …

Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain leads …

Objective To prospectively evaluate safety and efficacy of brain-responsive neurostimulation
in adults with medically intractable focal onset seizures (FOS) over 9 years. Methods Adults …

Objective To describe clinical characteristics and immunotherapy responses in patients with
autoimmune epilepsy. Design Observational, retrospective case series. Setting Mayo Clinic …

Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans have …

Objective Evaluate the seizure‐reduction response and safety of mesial temporal lobe ( MTL
) brain‐responsive stimulation in adults with medically intractable partial‐onset seizures of …

Memory failures are frustrating and often the result of ineffective encoding. One approach to
improving memory outcomes is through direct modulation of brain activity with electrical …

Purpose: To determine the long‐term efficacy of anterior temporal lobectomy for medically
refractory temporal lobe epilepsy in patients with nonlesional magnetic resonance imaging (…