User profiles for Graeme Moffat

Graeme Moffat

System 2 Neurotechnology & University of Toronto
Verified email at utoronto.ca
Cited by 1277

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2 …

…, CJ Henderson, CR Wolf, GJ Moffat… - Biochemical …, 2002 - portlandpress.com
Mice that lack the Nrf2 basic-region leucine-zipper transcription factor are more sensitive
than wild-type (WT) animals to the cytotoxic and genotoxic effects of foreign chemicals and …

[HTML][HTML] Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift

LE Roberts, G Moffat, M Baumann, LM Ward… - Journal of the …, 2008 - Springer
Animals exposed to noise trauma show augmented synchronous neural activity in
tonotopically reorganized primary auditory cortex consequent on hearing loss. Diminished …

Residual inhibition functions in relation to tinnitus spectra and auditory threshold shift

LE Roberts, G Moffat, DJ Bosnyak - Acta Oto-Laryngologica, 2006 - Taylor & Francis
Conclusions: Psychoacoustic functions relating the depth and duration of tinnitus suppression
(‘residual inhibition’) to the center frequency of band-passed noise masking sounds …

Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the …

VP Kelly, EM Ellis, MM Manson, SA Chanas, GJ Moffat… - Cancer Research, 2000 - AACR
Structurally diverse compounds can confer resistance to aflatoxin B 1 (AFB 1 ) hepatocarcinogenesis
in the rat. Treatment with either phytochemicals [benzyl isothiocyanate, coumarin(…

[HTML][HTML] Attentional and affective consequences of technology supported mindfulness training: a randomised, active control, efficacy trial

S Bhayee, P Tomaszewski, DH Lee, G Moffat, L Pino… - BMC psychology, 2016 - Springer
Background Mindfulness training (MT) programs represent an approach to attention training
with well-validated mental health benefits. However, research supporting MT efficacy is …

The Practical Application of Three Validated In Vitro Embryotoxicity Tests: The Report and Recommendations of an ECVAM/ZEBET Workshop (ECVAM Workshop 57)

…, E Faustman, U Haas, GJ Moffat… - Alternatives to …, 2006 - journals.sagepub.com
In line with the recommendations of an ECVAM workshop on reproductive toxicity, held in
1994 (1), ECVAM initiated and funded a validation study of three in vitro embryotoxicity tests. In …

Characterizing population EEG dynamics throughout adulthood

A Hashemi, LJ Pino, G Moffat, KJ Mathewson… - ENeuro, 2016 - eneuro.org
For decades, electroencephalography (EEG) has been a useful tool for investigating the
neural mechanisms underlying human psychological processes. However, the amount of time …

Pi-class glutathione S-transferase: regulation and function

CJ Henderson, AW McLaren, GJ Moffat… - Chemico-Biological …, 1998 - Elsevier
Our laboratory has been involved in the study of Glutathione S-transferase pi (GST pi) for
many years, both in terms of regulation of gene expression and in trying to understand the …

Self-supervised representation learning from electroencephalography signals

…, I Albuquerque, A Hyvärinen, G Moffat… - 2019 IEEE 29th …, 2019 - ieeexplore.ieee.org
The supervised learning paradigm is limited by the cost - and sometimes the impracticality -
of data collection and labeling in multiple domains. Self-supervised learning, a paradigm …

Structural features of the human C3 gene: intron/exon organization, transcriptional start site, and promoter region sequence

DP Vik, P Amiguet, GJ Moffat, M Fey… - Biochemistry, 1991 - ACS Publications
1 kilobase pair (kb) of the C3 gene. The remainder of the gene was cloned by using the
polymerase chain reaction. These clones were used to identify the intron/exon boundaries and …