User profiles for Graeme Moffat
Graeme MoffatSystem 2 Neurotechnology & University of Toronto Verified email at utoronto.ca Cited by 1277 |
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2 …
…, CJ Henderson, CR Wolf, GJ Moffat… - Biochemical …, 2002 - portlandpress.com
Mice that lack the Nrf2 basic-region leucine-zipper transcription factor are more sensitive
than wild-type (WT) animals to the cytotoxic and genotoxic effects of foreign chemicals and …
than wild-type (WT) animals to the cytotoxic and genotoxic effects of foreign chemicals and …
[HTML][HTML] Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift
Animals exposed to noise trauma show augmented synchronous neural activity in
tonotopically reorganized primary auditory cortex consequent on hearing loss. Diminished …
tonotopically reorganized primary auditory cortex consequent on hearing loss. Diminished …
Residual inhibition functions in relation to tinnitus spectra and auditory threshold shift
Conclusions: Psychoacoustic functions relating the depth and duration of tinnitus suppression
(‘residual inhibition’) to the center frequency of band-passed noise masking sounds …
(‘residual inhibition’) to the center frequency of band-passed noise masking sounds …
Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the …
VP Kelly, EM Ellis, MM Manson, SA Chanas, GJ Moffat… - Cancer Research, 2000 - AACR
Structurally diverse compounds can confer resistance to aflatoxin B 1 (AFB 1 ) hepatocarcinogenesis
in the rat. Treatment with either phytochemicals [benzyl isothiocyanate, coumarin(…
in the rat. Treatment with either phytochemicals [benzyl isothiocyanate, coumarin(…
[HTML][HTML] Attentional and affective consequences of technology supported mindfulness training: a randomised, active control, efficacy trial
Background Mindfulness training (MT) programs represent an approach to attention training
with well-validated mental health benefits. However, research supporting MT efficacy is …
with well-validated mental health benefits. However, research supporting MT efficacy is …
The Practical Application of Three Validated In Vitro Embryotoxicity Tests: The Report and Recommendations of an ECVAM/ZEBET Workshop (ECVAM Workshop 57)
…, E Faustman, U Haas, GJ Moffat… - Alternatives to …, 2006 - journals.sagepub.com
In line with the recommendations of an ECVAM workshop on reproductive toxicity, held in
1994 (1), ECVAM initiated and funded a validation study of three in vitro embryotoxicity tests. In …
1994 (1), ECVAM initiated and funded a validation study of three in vitro embryotoxicity tests. In …
Characterizing population EEG dynamics throughout adulthood
For decades, electroencephalography (EEG) has been a useful tool for investigating the
neural mechanisms underlying human psychological processes. However, the amount of time …
neural mechanisms underlying human psychological processes. However, the amount of time …
Pi-class glutathione S-transferase: regulation and function
CJ Henderson, AW McLaren, GJ Moffat… - Chemico-Biological …, 1998 - Elsevier
Our laboratory has been involved in the study of Glutathione S-transferase pi (GST pi) for
many years, both in terms of regulation of gene expression and in trying to understand the …
many years, both in terms of regulation of gene expression and in trying to understand the …
Self-supervised representation learning from electroencephalography signals
The supervised learning paradigm is limited by the cost - and sometimes the impracticality -
of data collection and labeling in multiple domains. Self-supervised learning, a paradigm …
of data collection and labeling in multiple domains. Self-supervised learning, a paradigm …
Structural features of the human C3 gene: intron/exon organization, transcriptional start site, and promoter region sequence
DP Vik, P Amiguet, GJ Moffat, M Fey… - Biochemistry, 1991 - ACS Publications
1 kilobase pair (kb) of the C3 gene. The remainder of the gene was cloned by using the
polymerase chain reaction. These clones were used to identify the intron/exon boundaries and …
polymerase chain reaction. These clones were used to identify the intron/exon boundaries and …