This is a revision of guidelines, originally published in 2004, for the assessment of patients
with neuropathic pain. Neuropathic pain is defined as pain arising as a direct consequence of …

Neuroimaging and neurophysiological studies have shown that nociceptive stimuli elicit
responses in an extensive cortical network including somatosensory, insular and cingulate areas…

Pain is a conscious experience, crucial for survival. To investigate the neural basis of pain
perception in humans, a large number of investigators apply noxious stimuli to the body of …

The combination of functional magnetic resonance imaging (FMRI) and electroencephalography
(EEG) has received much recent attention, since it potentially offers a new tool for …

Functional neuroimaging studies in humans have shown that nociceptive stimuli elicit activity
in a wide network of cortical areas commonly labeled as the “pain matrix” and thought to be …

Internally and externally triggered sensory, motor and cognitive events elicit a number of
transient changes in the ongoing electroencephalogram (EEG): event-related brain potentials (…

Although laser-evoked electroencephalographic (EEG) responses are increasingly used to
investigate nociceptive pathways, their functional significance remains unclear. The …

Brief radiant laser pulses can be used to activate cutaneous Aδ and C nociceptors selectively
and elicit a number of transient brain responses [laser-evoked potentials (LEPs)] in the …

Objective Tactile spatial acuity is routinely tested in neurology to assess the state of the
dorsal column system. In contrast, spatial acuity for pain is not assessed, having never been …

Chronic pain is the greatest source of disability globally and claims related to chronic pain
feature in many insurance and medico-legal cases. Brain imaging (for example, functional MRI…