User profiles for F. Charron
Frederic CharronProfessor, IRCM, University of Montreal, McGill University Verified email at ircm.qc.ca Cited by 10474 |
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
…, M Bernard, J Van Horssen, HE De Vries, F Charron… - Science, 2011 - science.org
The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed …
perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed …
GATA transcription factors and cardiac development
Three members of the GATA family of transcription factors, GATA-4, -5, and -6, are expressed
in the developing heart. One family member, GATA-5, is restricted to the endocardium …
in the developing heart. One family member, GATA-5, is restricted to the endocardium …
Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance
F Charron, M Tessier-Lavigne - 2005 - journals.biologists.com
… in commissural neurons Commissural axons invade the motor columns Charron et al., 2003
… in commissural neurons Commissural axons invade the motor columns Charron et al., 2003 …
… in commissural neurons Commissural axons invade the motor columns Charron et al., 2003 …
[HTML][HTML] A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
Heterozygous Tbx5 del/+ mice were generated to study the mechanisms by which TBX5
haploinsufficiency causes cardiac and forelimb abnormalities seen in Holt-Oram syndrome. …
haploinsufficiency causes cardiac and forelimb abnormalities seen in Holt-Oram syndrome. …
[HTML][HTML] The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors
… (F.Charron et al., unpublished results). Interestingly, neither GATA‐1 nor GATA‐6, which do
not transcriptionally synergize with Nkx2‐5, could be retained on the MBP–Nkx2‐5 column, …
not transcriptionally synergize with Nkx2‐5, could be retained on the MBP–Nkx2‐5 column, …
[HTML][HTML] The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance
Developing axons are guided to their targets by attractive and repulsive guidance cues. In
the embryonic spinal cord, the floor plate chemoattractant Netrin-1 is required to guide …
the embryonic spinal cord, the floor plate chemoattractant Netrin-1 is required to guide …
[HTML][HTML] Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons
Axon outgrowth is the first step in the formation of neuronal connections, but the pathways
that regulate axon extension are still poorly understood. We find that mice deficient in …
that regulate axon extension are still poorly understood. We find that mice deficient in …
[HTML][HTML] GATA-dependent recruitment of MEF2 proteins to target promoters
The myocyte enhancer factor-2 (MEF2) proteins are MADS-box transcription factors that are
essential for differentiation of all muscle lineages but their mechanisms of action remain …
essential for differentiation of all muscle lineages but their mechanisms of action remain …
Detecting anomalous and unknown intrusions against programs
AK Ghosh, J Wanken, F Charron - Proceedings 14th annual …, 1998 - ieeexplore.ieee.org
The ubiquity of the Internet connection to desktops has been both a boon to business as well
as a cause for concern for the security of digital assets that may be unknowingly exposed. …
as a cause for concern for the security of digital assets that may be unknowingly exposed. …
Boc is a receptor for sonic hedgehog in the guidance of commissural axons
… Tian and F. de Sauvage for discussions during early stages of the project; and T. … Ami
Okada and Frédéric Charron: These authors contributed equally to this work. … Frédéric Charron …
Okada and Frédéric Charron: These authors contributed equally to this work. … Frédéric Charron …