User profiles for Eshwar Udho

Eshwar B Udho

Promega Corporation
Verified email at promega.com
Cited by 698

[HTML][HTML] PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation

F Liang, J Liang, WQ Wang, JP Sun, E Udho… - Journal of biological …, 2007 - ASBMB
Phosphatase of regenerating liver 3 (PRL3) is overexpressed in a variety of tumors, and high
levels of PRL3 expression are associated with tumorigenesis and metastasis. Consistent …

[PDF][PDF] Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis

…, D Wojtowicz, W Liu, N Noinaj, TJ Barnard, E Udho… - Structure, 2012 - cell.com
Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria.
They contain C-terminal extracellular passenger domains that are involved in adhesion to …

A combination antioxidant therapy to inhibit NOX2 and activate Nrf2 decreases secondary brain damage and improves functional recovery after traumatic brain injury

…, TH Kim, SL Mehta, E Udho… - Journal of Cerebral …, 2018 - journals.sagepub.com
Uncontrolled oxidative stress contributes to the secondary neuronal death that promotes
long-term neurological dysfunction following traumatic brain injury (TBI). Surprisingly, both …

[PDF][PDF] Protein translocation through anthrax toxin channels formed in planar lipid bilayers

S Zhang, E Udho, Z Wu, RJ Collier, A Finkelstein - Biophysical journal, 2004 - cell.com
The 63-kDa fragment of the protective antigen (PA) component of anthrax toxin forms a
heptameric channel, (PA 63 ) 7 , in acidic endosomal membranes that leads to the translocation …

ERα signaling is required for TrkB-mediated hippocampal neuroprotection in female neonatal mice after hypoxic ischemic encephalopathy

U Cikla, V Chanana, DB Kintner, E Udho, J Eickhoff… - eneuro, 2016 - eneuro.org
Male neonate brains are more susceptible to the effects of perinatal asphyxia resulting in
hypoxia and ischemia (HI)-related brain injury. The relative resistance of female neonatal …

[HTML][HTML] A highly sensitive pan-cancer test for microsatellite instability

JW Bacher, EB Udho, EE Strauss, I Vyazunova… - The Journal of Molecular …, 2023 - Elsevier
Microsatellite instability (MSI) is an evolving biomarker for cancer detection and treatment.
MSI was first used to identify patients with Lynch syndrome, a hereditary form of colorectal …

PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity

E Udho, VC Tedesco, A Zygmunt, NA Krucher - … and biophysical research …, 2002 - Elsevier
Protein phosphatase type 1 catalytic subunit (PP1c) is a serine/threonine phosphatase involved
in the dephosphorylation of many proteins in eukaryotic cells. It associates with several …

Reconstitution of bacterial outer membrane TonB-dependent transporters in planar lipid bilayer membranes

E Udho, KS Jakes, SK Buchanan… - Proceedings of the …, 2009 - National Acad Sciences
Micronutrients such as siderophore-bound iron and vitamin B 12 cross the outer membrane
of Gram-negative bacteria through a group of 22-stranded β-barrel proteins. They share the …

Hypoxia stimulates p16 expression and association with cdk4

A Zygmunt, VC Tedesco, E Udho, NA Krucher - Experimental cell research, 2002 - Elsevier
Exposure of CV-1P cells to hypoxic conditions causes cell proliferation inhibition concomitant
with the accumulation of pRb in the hypophosphorylated, growth suppressive form. This is …

[HTML][HTML] Attenuation of retinal vascular development in neonatal mice subjected to hypoxic-ischemic encephalopathy

IS Zaitoun, U Cikla, D Zafer, E Udho, R Almomani… - Scientific reports, 2018 - nature.com
A significant proportion of children that survive hypoxic-ischemic encephalopathy (HIE)
develop visual impairment. These visual deficits are generally attributed to injuries that occur in …