High-frequency ripple oscillations, observed most prominently in the hippocampal CA1
pyramidal layer, are associated with memory consolidation. The cellular and network …

We report a scalable method to monolithically integrate microscopic light emitting diodes (μLEDs)
and recording sites onto silicon neural probes for optogenetic applications in …

Low intensity electric fields have been suggested to affect the ongoing neuronal activity in
vitro and in human studies. However, the physiological mechanism of how weak electrical …

Both circuit and single-cell properties contribute to network rhythms. In vitro, pyramidal cells
exhibit theta-band membrane potential (subthreshold) resonance, but whether and how …

To understand how function arises from the interactions between neurons, it is necessary to
use methods that allow the monitoring of brain activity at the single-neuron, single-spike …

Monitoring representative fractions of neurons from multiple brain circuits in behaving animals
is necessary for understanding neuronal computation. Here, we describe a system that …

Previous studies have shown that intracortical activity can be used to operate prosthetic
devices such as an artificial limb. Previously used neuronal signals were either the activity of …

Neostriatal cholinergic interneurons are believed to be important for reinforcement-mediated
learning and response selection by signaling the occurrence and motivational value of …

Neuronal control with high temporal precision is possible with optogenetics, yet currently
available methods do not enable to control independently multiple locations in the brains of …

Objective. Optogenetics promises exciting neuroscience research by offering optical stimulation
of neurons with unprecedented temporal resolution, cell-type specificity and the ability to …