Reaction of dipeptides with N-bromosuccinimide results in selective α-bromination of
glycine residues. Subsequent reactions of brominated peptides with diethyl malonate and …

Retinal transducin was previously shown to be farnesylated on its gamma subunit. This
farnesylation reaction on a cysteine residue near the carboxyl terminus is followed by peptidase …

The free-radical reactions of a range of amino acid derivatives with IV-bromosuccinimide are
described. The products and relative rates of these reactionsindicate that the-position of an …

Revised Manuscript Received March 12, 1992 abstract: Proteins from eucaryotic cells which
have a carboxyl-terminal CAAX motif are posttranslationally modified by isoprenylation. The …

Proteins that are post-translationally modified by prenylation can be either farnesylated (C-15)
or geranylgeranylated (C-20) by separate prenyltransferase enzymes. Prenylated proteins …

Bifunctional compounds were tested in vitro as potential inhibitors of pig liver catechol-O-methyltransferase
(COMT) with respect to the catechol substrate 4-[(3,4-dihydroxyphenyl)azo]…

An enantioselective 1,2-chlorine atom migration was observed in the tributyltin hydride
reduction of various dihalogenated dihydrocinnamic acid derivatives. It is proposed that the …

Science disengagement amongst school children remains a global challenge, leading to
calls for more scientists to engage with the public. Here the authors discuss how a voluntary, …

Abstract Treatment of N-phthaloyl-α-amino acid methyl esters with N-bromosuccinimide,
followed by reaction with silver nitrate in aqueous acetone, affords homochiral hydroxy-(α-…

Two progressive series of molecules with two polyhydroxybenzamide substructures were
synthesized and tested as potential inhibitors of catechol-O-methyltransferase (COMT). These …