User profiles for Ditte Dencker
Ditte Dencker ThorbekPost Doc, Neuropsykiatrisk Laboratorium Verified email at regionh.dk Cited by 1149 |
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
J Jeon, D Dencker, G Wörtwein… - Journal of …, 2010 - Soc Neuroscience
Acetylcholine (ACh) regulates many key functions of the CNS by activating cell surface
receptors referred to as muscarinic ACh receptors (M 1 –M 5 mAChRs). Like other mAChR …
receptors referred to as muscarinic ACh receptors (M 1 –M 5 mAChRs). Like other mAChR …
Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents
Positive allosteric modulators (PAMs) of the M 4 muscarinic acetylcholine receptor (mAChR)
represent a novel approach for the treatment of psychotic symptoms associated with …
represent a novel approach for the treatment of psychotic symptoms associated with …
Major femoral vascular access complications after coronary diagnostic and interventional procedures: a Danish register study
D Dencker, F Pedersen, T Engstrøm, L Køber… - International Journal of …, 2016 - Elsevier
Background Vascular access complications after coronary angiography (CAG) and percutaneous
coronary intervention (PCI) are known to increase morbidity, prolong hospitalization …
coronary intervention (PCI) are known to increase morbidity, prolong hospitalization …
Muscarinic acetylcholine receptor subtypes as potential drug targets for the treatment of schizophrenia, drug abuse, and Parkinson's disease
The neurotransmitter dopamine plays important roles in modulating cognitive, affective, and
motor functions. Dysregulation of dopaminergic neurotransmission is thought to be involved …
motor functions. Dysregulation of dopaminergic neurotransmission is thought to be involved …
The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice
Glucagon-like peptide-1 (GLP-1) is a gut peptide that regulates food intake and glucose
metabolism. GLP-1 is also produced and released in the brain, and GLP-1 receptors are …
metabolism. GLP-1 is also produced and released in the brain, and GLP-1 receptors are …
Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice
Rationale The reinforcing effects of cocaine are mediated by the mesolimbic dopamine system.
Behavioral and neurochemical studies have shown that the cholinergic muscarinic M 4 …
Behavioral and neurochemical studies have shown that the cholinergic muscarinic M 4 …
Role for the M1 Muscarinic Acetylcholine Receptor in Top-Down Cognitive Processing Using a Touchscreen Visual Discrimination Task in Mice
RW Gould, D Dencker, M Grannan… - ACS chemical …, 2015 - ACS Publications
The M 1 muscarinic acetylcholine receptor (mAChR) subtype has been implicated in the
underlying mechanisms of learning and memory and represents an important potential …
underlying mechanisms of learning and memory and represents an important potential …
Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor
A Fink-Jensen, LS Schmidt, D Dencker… - European journal of …, 2011 - Elsevier
A delicate balance exists between the central dopaminergic and cholinergic neurotransmitter
systems with respect to motor function. An imbalance can result in motor dysfunction as …
systems with respect to motor function. An imbalance can result in motor dysfunction as …
Physiological roles of CNS muscarinic receptors gained from knockout mice
Because the five muscarinic acetylcholine receptor subtypes have overlapping distributions
in many CNS tissues, and because ligands with a high degree of selectivity for a given …
in many CNS tissues, and because ligands with a high degree of selectivity for a given …
Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist …
Disturbances in central dopaminergic neurotransmission are believed to be centrally involved
in the pathogenesis of schizophrenia. Central dopaminergic and cholinergic systems …
in the pathogenesis of schizophrenia. Central dopaminergic and cholinergic systems …