Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) TH1-like responses.
We have characterized the progressive stages of chronic intestinal inflammation that develops
spontaneously in specific pathogen-free (SPF) mice with a targeted disruption in the IL-10 …
spontaneously in specific pathogen-free (SPF) mice with a targeted disruption in the IL-10 …
Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.
Previous studies in vivo have shown that IL-10 infusion can prevent lethal endotoxic shock.
Mice deficient in the production of IL-10 (IL10T) were used to investigate the regulatory role …
Mice deficient in the production of IL-10 (IL10T) were used to investigate the regulatory role …
T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.
Mice rendered deficient in the production of interleukin 10 (IL-10-/-) develop a chronic
inflammatory bowel disease (IBD) that predominates in the colon and shares histopathological …
inflammatory bowel disease (IBD) that predominates in the colon and shares histopathological …
[PDF][PDF] O2⋅− and H2O2-mediated disruption of Fe metabolism causes the differential susceptibility of NSCLC and GBM cancer cells to pharmacological ascorbate
…, MC Smith, TA Hejleh, DJ Berg, J Zhang, J Keech… - Cancer cell, 2017 - cell.com
Pharmacological ascorbate has been proposed as a potential anti-cancer agent when
combined with radiation and chemotherapy. The anti-cancer effects of ascorbate are …
combined with radiation and chemotherapy. The anti-cancer effects of ascorbate are …
Selected contribution: Hyperthermia-induced intestinal permeability and the role of oxidative and nitrosative stress
GP Lambert, CV Gisolfi, DJ Berg… - Journal of applied …, 2002 - journals.physiology.org
The purpose of this study was to characterize intestinal permeability changes over a range
of physiologically relevant body temperatures in vivo and in vitro. Initially, FITC-dextran (4,000 …
of physiologically relevant body temperatures in vivo and in vitro. Initially, FITC-dextran (4,000 …
Rapid development of colitis in NSAID-treated IL-10–deficient mice
DJ Berg, J Zhang, JV Weinstock, HF Ismail, KA Earle… - Gastroenterology, 2002 - Elsevier
Background & Aims: Interleukin (IL)-10 is an anti-inflammatory and immune regulatory
cytokine. IL-10–deficient mice (IL-10 −/− ) develop chronic inflammatory bowel disease (IBD), …
cytokine. IL-10–deficient mice (IL-10 −/− ) develop chronic inflammatory bowel disease (IBD), …
[BOOK][B] Multithreaded programming with Pthreads
B Lewis, DJ Berg - 1998 - dl.acm.org
The POSIX threads (Pthreads) library is a thread API for C/C++ to control parallel threads
and spawn concurrent process flows. Programming in Pthreads usually suffers from …
and spawn concurrent process flows. Programming in Pthreads usually suffers from …
Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.
DJ Berg, MW Leach, R Kühn, K Rajewsky… - The Journal of …, 1995 - rupress.org
We have examined the role of endogenously produced interleukin (IL) 4 and IL-10 in the
regulation of inflammatory and immune reactions in the skin. In these experiments, irritant and …
regulation of inflammatory and immune reactions in the skin. In these experiments, irritant and …
Consuming a ketogenic diet while receiving radiation and chemotherapy for locally advanced lung cancer and pancreatic cancer: the University of Iowa experience of …
…, TA Hejleh, GH Clamon, DJ Berg… - Radiation …, 2017 - meridian.allenpress.com
Ketogenic diets are low in carbohydrates and high in fat, which forces cells to rely more
heavily upon mitochondrial oxidation of fatty acids for energy. Relative to normal cells, cancer …
heavily upon mitochondrial oxidation of fatty acids for energy. Relative to normal cells, cancer …
R-spondin1, a novel intestinotrophic mitogen, ameliorates experimental colitis in mice
…, P Shinkawa, KA Kim, Y Liu, MD Levy, DJ Berg… - Gastroenterology, 2007 - Elsevier
Background & Aims: R-spondin 1 (Rspo1) is a novel epithelial mitogen that stimulates the
growth of mucosa in both the small and large intestine. Methods: We investigated the …
growth of mucosa in both the small and large intestine. Methods: We investigated the …