User profiles for D. N. Linsenbardt

David Linsenbardt

University of New Mexico - School of Medicine - Dept. of Neurosciences
Verified email at salud.unm.edu
Cited by 1160

Adolescent C57BL/6J (but not DBA/2J) mice consume greater amounts of limited‐access ethanol compared to adults and display continued elevated ethanol intake …

EM Moore, JN Mariani, DN Linsenbardt… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Alcohol use is common during the adolescent period, a time at which a number
of crucial neurobiological, hormonal, and behavioral changes occur ( Spear, 2000 ). In …

Sensitivity and tolerance to the hypnotic and ataxic effects of ethanol in adolescent and adult C57BL/6J and DBA/2J mice

DN Linsenbardt, EM Moore, CD Gross… - Alcoholism: Clinical …, 2009 - Wiley Online Library
Background: There is considerable research examining differences in adolescent and adult
sensitivity and tolerance to ethanol related behavioral phenotypes. However, the available …

Using drinking in the dark to model prenatal binge‐like exposure to ethanol in C57BL/6J mice

…, AM Cavelli, E Gigante, DN Linsenbardt - … : The Journal of the …, 2008 - Wiley Online Library
Animal models of prenatal ethanol exposure are necessary to more fully understand the
effects of ethanol on the developing embryo/fetus. However, most models employ procedures …

Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area

DN Linsenbardt, SL Boehm II - Neuroscience, 2009 - Elsevier
Recent studies have indicated a role for the endocannabinoid system in the behavioral and
physiological effects of alcohol (ethanol), particularly ethanol seeking behaviors. However, …

Alterations in the rate of binge ethanol consumption: implications for preclinical studies in mice

DN Linsenbardt, SL Boehm - Addiction biology, 2014 - Wiley Online Library
The rate at which alcohol (ethanol) is consumed has direct impact on its behavioral and
subjective effects. For this reason, alterations in the pattern of ethanol consumption as a function …

GABAergic modulation of binge-like ethanol intake in C57BL/6J mice

…, KJ Goldfarb, S Stepanovska, DN Linsenbardt… - Pharmacology …, 2007 - Elsevier
GABA receptor systems have long been implicated in alcoholism, and GABAergic drugs have
demonstrated efficacy in altering alcohol intake in some rodent models. The present study …

Habitual behavior is mediated by a shift in response-outcome encoding by infralimbic cortex

JM Barker, WB Glen, DN Linsenbardt, CC Lapish… - eneuro, 2017 - eneuro.org
The ability to flexibly switch between goal-directed actions and habits is critical for adaptive
behavior. The infralimbic prefrontal cortex (IfL-C) has been consistently identified as a crucial …

Tolerance to Ethanol's Ataxic Effects and Alterations in Ethanol‐Induced Locomotion Following Repeated Binge‐Like Ethanol Intake Using the DID Model

DN Linsenbardt, EM Moore, KD Griffin… - Alcoholism: Clinical …, 2011 - Wiley Online Library
Background: Tolerance to the behavioral and subjective effects of alcohol (ethanol) is thought
to be a major predictive factor for the development of alcoholism. Evidence from rodent …

[HTML][HTML] The RNA-binding protein HuD regulates alternative splicing and alternative polyadenylation in the mouse neocortex

…, JL Twiss, AS Gardiner, M Dell'Orco, DN Linsenbardt… - Molecules, 2021 - mdpi.com
The neuronal Hu/ELAV-like proteins HuB, HuC and HuD are a class of RNA-binding proteins
that are crucial for proper development and maintenance of the nervous system. These …

Ontogenetic differences in adolescent and adult C57BL/6J and DBA/2J mice: Anxiety‐like, locomotor, and consummatory behaviors

EM Moore, DN Linsenbardt, LC Melón… - Developmental …, 2011 - Wiley Online Library
… However, very few studies have utilized these strains during adolescence, and only two
studies to date have compared these two strains during adolescence (Linsenbardt, Moore, Gross…