User profiles for D. F. Marker
Daniel MarkerAssistant Professor of Neuropathology Verified email at upmc.edu Cited by 906 |
Methodologies for surveying herpetofauna mortality on rural highways
…, EK Crowe, C Mangan, DF Marker… - The Journal of …, 2007 - Wiley Online Library
Road mortality can contribute to local and regional declines in amphibian and reptile populations.
Thus, there is a need to accurately and efficiently identify hotspots of road‐mortality for …
Thus, there is a need to accurately and efficiently identify hotspots of road‐mortality for …
[HTML][HTML] Human papillomavirus type 16 E6 and E 7 proteins alter NF-kB in cultured cervical epithelial cells and inhibition of NF-kB promotes cell growth and …
ER Vandermark, KA Deluca, CR Gardner, DF Marker… - Virology, 2012 - Elsevier
The NF-kB family of transcription factors regulates important biological functions including cell
growth, survival and the immune response. We found that Human Papillomavirus type 16 (…
growth, survival and the immune response. We found that Human Papillomavirus type 16 (…
[HTML][HTML] LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein
DF Marker, JM Puccini, TE Mockus, J Barbieri… - Journal of …, 2012 - Springer
… When we examined these cells using ICC, we found the presence of some inclusions
that stained positive for neuronal markers, but these inclusions were much smaller and …
that stained positive for neuronal markers, but these inclusions were much smaller and …
Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3
…, S Pollack, O Polesskaya, DF Marker… - Journal of medicinal …, 2013 - ACS Publications
Inhibition of mixed lineage kinase 3 (MLK3) is a potential strategy for treatment of Parkinson’s
disease and HIV-1 associated neurocognitive disorders (HAND), requiring an inhibitor that …
disease and HIV-1 associated neurocognitive disorders (HAND), requiring an inhibitor that …
The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated …
DF Marker, MÈ Tremblay, JM Puccini… - Journal of …, 2013 - Soc Neuroscience
… We stained for the neutrophil marker 7/4 (white), GFP (green), which was present only in
monocytes derived from the peripheral bone marrow, and the monocyte/microglia marker Iba-1 (…
monocytes derived from the peripheral bone marrow, and the monocyte/microglia marker Iba-1 (…
Germ cell tumors of the central nervous system: a brief review and site-specific considerations
DF Marker, TM Pearce - Seminars in Diagnostic Pathology, 2023 - Elsevier
… Diagnosis should involve review of the clinical history, imaging studies, and assessment
of serum and cerebrospinal fluid tumor markers. Current therapeutic strategies involving …
of serum and cerebrospinal fluid tumor markers. Current therapeutic strategies involving …
A thin-skull window technique for chronic two-photon in vivo imaging of murine microglia in models of neuroinflammation
Traditionally in neuroscience, in vivo two photon imaging of the murine central nervous
system has either involved the use of open-skull1,2 or thinned-skull 3 preparations. While the …
system has either involved the use of open-skull1,2 or thinned-skull 3 preparations. While the …
Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders
JM Puccini, DF Marker, T Fitzgerald… - Journal of …, 2015 - Soc Neuroscience
Leucine-rich repeat kinase 2 (LRRK2) is the single most common genetic cause of both
familial and sporadic Parkinson's disease (PD), both of which share pathogenetic and …
familial and sporadic Parkinson's disease (PD), both of which share pathogenetic and …
[HTML][HTML] HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells
Despite the ability of combination antiretroviral treatment (cART) to reduce viral burden to
nearly undetectable levels in cerebrospinal fluid and serum, HIV-1 associated neurocognitive …
nearly undetectable levels in cerebrospinal fluid and serum, HIV-1 associated neurocognitive …
[HTML][HTML] Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas
DF Marker, TM Pearce - Acta Neuropathologica Communications, 2020 - Springer
… In conclusion, CDKN2A homozygous deletion is a marker of poor prognosis in histologic
grade 4 IDHm astrocytomas, but the impact of this finding in histologic grades 2 and 3 tumors is …
grade 4 IDHm astrocytomas, but the impact of this finding in histologic grades 2 and 3 tumors is …