User profiles for Christophe J. Dubois

Christophe J. DUBOIS

RMSB, UMR 5536 - University of Bordeaux
Verified email at rmsb.u-bordeaux.fr
Cited by 300

[HTML][HTML] A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle …

…, B Rodriguez-Grande, JB Lee, CJ Dubois… - Acta neuropathologica …, 2023 - Springer
Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and
its mild severity represents the most frequent cases. Moderate and severe injuries as well as …

[HTML][HTML] GluN2D NMDA receptors gate fear extinction learning and interneuron plasticity

CJ Dubois, SJ Liu - Frontiers in Synaptic Neuroscience, 2021 - frontiersin.org
The cerebellum is critically involved in the formation of associative fear memory and in
subsequent extinction learning. Fear conditioning is associated with a long-term potentiation at …

Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart–brain dysfunctions in adulthood

…, C Bernis, R Rouland, CJ Dubois, J Badaut… - Acta …, 2023 - Wiley Online Library
Aim Retrospective studies suggest that mild traumatic brain injury (mTBI) in pediatric
patients may lead to an increased risk of cardiac events. However, the exact functional and …

[HTML][HTML] Inhibitory neurotransmission drives endocannabinoid degradation to promote memory consolidation

CJ Dubois, J Fawcett-Patel, PA Katzman… - Nature …, 2020 - nature.com
Endocannabinoids retrogradely regulate synaptic transmission and their abundance is
controlled by the fine balance between endocannabinoid synthesis and degradation. While the …

Presynaptic GluN2D receptors detect glutamate spillover and regulate cerebellar GABA release

CJ Dubois, PM Lachamp, L Sun… - Journal of …, 2016 - journals.physiology.org
Glutamate directly activates N-methyl-d-aspartate (NMDA) receptors on presynaptic inhibitory
interneurons and enhances GABA release, altering the excitatory-inhibitory balance within …

Role of the K+-Cl–Cotransporter KCC2a Isoform in Mammalian Respiration at Birth

CJ Dubois, L Cardoit, V Schwarz, M Markkanen… - ENeuro, 2018 - eneuro.org
In central respiratory circuitry, synaptic excitation is responsible for synchronizing neuronal
activity in the different respiratory rhythm phases, whereas chloride-mediated inhibition is …

[HTML][HTML] Perinatal development of central vestibular neurons in mice

CJ Dubois, L Cardoit, J Simmers, FM Lambert… - Frontiers in …, 2022 - frontiersin.org
Central circuitry of the vestibular nuclei integrates sensory inputs in the adaptive control of
motor behaviors such as posture, locomotion, and gaze stabilization. Thus far, such circuits …

Perinatal exposure to ethanol in rats induces permanent disturbances of breathing and chemosensitivity during adulthood

CJ Dubois, O Pierrefiche - Neuroscience Letters, 2020 - Elsevier
Perinatal exposure to drugs of abuse, including alcohol (ethanol), is known to impinge the
development of respiratory function. However, most studies described the short-term effects of …

Endocannabinoid-mediated rescue of somatosensory cortex activity, plasticity and related behaviors following an early in life concussion.

…, M Malinconi, BP Noarbe, A Obenaus, CJ Dubois - bioRxiv, 2024 - biorxiv.org
Due to the assumed plasticity of immature brain, early in life brain alterations are thought to
lead to better recoveries in comparison to the mature brain. Despite clinical needs, how …

Stellate cells: synaptic processing and plasticity

SJ Liu, CJ Dubois - Handbook of the Cerebellum and Cerebellar …, 2021 - Springer
Stellate and basket cells in the molecular layer of the cerebellum are inhibitory interneurons
that control the activity of Purkinje cells. Recent studies using genetic approaches have …