O-GlcNAc is a widespread dynamic carbohydrate modification of cytosolic and nuclear
proteins with features analogous to phosphorylation. O-GlcNAc acts critically in many cellular …

Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative
diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant …

In the mammalian central nervous system, the structure known as the postsynaptic density (PSD)
is a dense complex of proteins whose function is to detect and respond to …

The strength of synaptic transmission is controlled by the number and activity of neurotransmitter
receptors. However, little is known about absolute numbers and densities of receptor …

Synaptic plasticity is dependent on the differential sorting, delivery and retention of neurotransmitter
receptors, but the mechanisms underlying these processes are poorly understood. …

The postsynaptic density (PSD) signaling machinery contains proteins with diverse functions.
Brain region-specific variations in PSD components mediate distinct physiological …

This paper presents Yellow Fluorescence-Activating and absorption-Shifting Tag (Y-FAST),
a small monomeric protein tag, half as large as the green fluorescent protein, enabling …

Abstract Development of the nervous system requires extensive axonal and dendritic
growth during which neurons massively increase their surface area. Here we report that the …

The actin cytoskeleton of dendritic spines plays a key role in morphological aspects of
synaptic plasticity. The detailed analysis of the spine structure and dynamics in live neurons, …

Diamond has a number of unique properties that make it an attractive electronic and bio-electronic
material. Here we show the ordered growth of mammalian neurons, the principal …