Adolescence is a time of significant neural and behavioral change with remarkable development
in social, emotional, and cognitive skills. It is also a time of increased exploration and …

A dramatic maturational process ongoing in adolescence is prefrontal cortex development,
including its dopamine innervation. Dopamine axons grow from the striatum to the prefrontal …

Low miR-218 expression in the medial prefrontal cortex (mPFC) is a consistent trait of
depression. Here we assessed whether miR-218 in the mPFC confers resilience or susceptibility …

Backgroud Variations in the expression of the Netrin-1 guidance cue receptor DCC (deleted
in colorectal cancer) appear to confer resilience or susceptibility to psychopathologies …

Background Dopaminergic input to the prefrontal cortex (PFC) increases throughout
adolescence and, by establishing precisely localized synapses, calibrates cognitive function. …

The mesocorticolimbic dopamine (DA) system is implicated in neurodevelopmental
psychiatric disorders including schizophrenia but it is unknown how disruptions in brain …

Axon guidance molecules direct growing axons toward their targets, assembling the intricate
wiring of the nervous system. One of these molecules, Netrin-1, and its receptor, DCC (…

Objective: to develop a Navigation Program for cancer patients, based on the model proposed
by The GW Cancer Institute at George Washington University, adapted to the reality of a …

Netrins are guidance cues involved in neural connectivity. We have shown that the netrin-1
receptor DCC (deleted in colorectal cancer) is involved in the functional organization of the …

The ultra-tight nature of shale reservoirs has resulted in the maximization of the stimulated
area within a section to increase production. As a result, some wells appear to interfere with …