User profiles for Catherine M. Cahill
Catherine CahillUCLA Verified email at ucla.edu Cited by 8254 |
[HTML][HTML] TNF-α and neuropathic pain-a review
Tumor necrosis factor alpha (TNF-α) was discovered more than a century ago, and its
known roles have extended from within the immune system to include a neuro-inflammatory …
known roles have extended from within the immune system to include a neuro-inflammatory …
Neuropathic pain: a practical guide for the clinician
Neuropathic pain, caused by various central and peripheral nerve disorders, is especially
problematic because of its severity, chronicity and resistance to simple analgesics. The …
problematic because of its severity, chronicity and resistance to simple analgesics. The …
[HTML][HTML] An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
JT Rogers, JD Randall, CM Cahill, PS Eder… - Journal of Biological …, 2002 - ASBMB
Iron-responsive elements (IREs) are the RNA stem loops that control cellular iron homeostasis
by regulating ferritin translation and transferrin receptor mRNA stability. We mapped a …
by regulating ferritin translation and transferrin receptor mRNA stability. We mapped a …
Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl− homeostasis
A major unresolved issue in treating pain is the paradoxical hyperalgesia produced by the
gold-standard analgesic morphine and other opiates. We found that hyperalgesia-inducing …
gold-standard analgesic morphine and other opiates. We found that hyperalgesia-inducing …
[HTML][HTML] Translation of the Alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5′-untranslated region sequences
JT Rogers, LM Leiter, J McPhee, CM Cahill… - Journal of Biological …, 1999 - ASBMB
The amyloid precursorprotein (APP) has been associated with Alzheimer's disease (AD)
because APP is processed into the β-peptide that accumulates in amyloid plaques, and APP …
because APP is processed into the β-peptide that accumulates in amyloid plaques, and APP …
The cognitive and neurophysiological basis of emotion dysregulation in bipolar disorder
BACKGROUND: Bipolar disorder is characterized by fluctuating affect and mood, and is
associated with specific neurocognitive deficits consistent with neuropathology in cerebello–…
associated with specific neurocognitive deficits consistent with neuropathology in cerebello–…
Prolonged morphine treatment targets δ opioid receptors to neuronal plasma membranes and enhances δ-mediated antinociception
CM Cahill, A Morinville, MC Lee… - Journal of …, 2001 - Soc Neuroscience
Opioid receptors are known to undergo complex regulatory changes in response to ligand
exposure. In the present study, we examined the effect of morphine on the in vitro and in vivo …
exposure. In the present study, we examined the effect of morphine on the in vitro and in vivo …
[HTML][HTML] Interleukin (IL) 1β induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT/IκB kinase α pathway targeting activator protein-1
CM Cahill, JT Rogers - Journal of Biological Chemistry, 2008 - ASBMB
Here we describe a novel role for the phosphatidylinositol 3-kinase/AKT pathway in
mediating induction of interleukin-6 (IL-6) in response to IL-1. Pharmacological inhibition of …
mediating induction of interleukin-6 (IL-6) in response to IL-1. Pharmacological inhibition of …
Increased abundance of opioid receptor heteromers after chronic morphine administration
The μ and δ types of opioid receptors form heteromers that exhibit pharmacological and
functional properties distinct from those of homomeric receptors. To characterize these …
functional properties distinct from those of homomeric receptors. To characterize these …
Pain and poppies: the good, the bad, and the ugly of opioid analgesics
Treating pain is one of the most difficult challenges in medicine and a key facet of disease
management. The isolation of morphine by Friedrich Sertürner in 1804 added an essential …
management. The isolation of morphine by Friedrich Sertürner in 1804 added an essential …