Mammalian TRIM67 functions in brain development and behavior

NP Boyer, C Monkiewicz, S Menon, SS Moy… - eneuro, 2018 - eneuro.org
Class I members of the tripartite motif (TRIM) family of E3 ubiquitin ligases evolutionarily
appeared just prior to the advent of neuronal like cells and have been implicated in neuronal …

TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching

…, CC Winkle, FL Urbina, C Monkiewicz… - Molecular biology of …, 2017 - Am Soc Cell Biol
Extracellular netrin-1 and its receptor deleted in colorectal cancer (DCC) promote axon
branching in developing cortical neurons. Netrin-dependent morphogenesis is preceded by …

The Class I E3 Ubiquitin Ligase TRIM67 Modulates Brain Development and Behavior

NP Boyer, C Monkiewicz, SS Moy, SL Gupton - bioRxiv, 2017 - biorxiv.org
Specific class I members of the TRIM family of E3 ubiquitin ligases have been implicated in
neuronal development from invertebrates to mammals. The single invertebrate class I TRIM …

Abbreviations used in this paper

…, S Menon, CC Winkle, FL Urbina, C Monkiewicz… - Am Soc Cell Biol
Extracellular netrin-1 and its receptor DCC promote axon branching in developing cortical
neurons. Netrin-dependent morphogenesis is preceded by multimerization of DCC …

A Pair of Trim Proteins Regulate Axon Guidance in Concert

NP Boyer - 2018 - search.proquest.com
… This includes all of our lab technicians; Charles Park, Christopher Carey Hanlin, Caroline
Monkiewicz and Vong Thoong: all of our undergraduate students; David Creasman, Maite …

[HTML][HTML] The ubiquitylome of developing cortical neurons

S Menon, D Goldfarb, EM Cousins… - Micropublication …, 2020 - ncbi.nlm.nih.gov
A) Graphical representation of approach. Embryonic day 15.5 (E15. 5) neurons were
dissected from the cortex of mice with indicated genotypes, and cultured for 56 hours prior to …

[PDF][PDF] The ubiquitylome of developing cortical neurons. microPublication Biology

S Menon, D Goldfarb, EM Cousins, MB Major… - 2020 - micropublication.org
A) Graphical representation of approach. Embryonic day 15.5 (E15. 5) neurons were
dissected from the cortex of mice with indicated genotypes, and cultured for 56 hours prior to …

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

S Menon, D Goldfarb, CT Ho, EW Cloer… - Molecular biology of …, 2021 - Am Soc Cell Biol
TRIM9 and TRIM67 are neuronally enriched E3 ubiquitin ligases essential for appropriate
morphogenesis of cortical and hippocampal neurons and fidelitous responses to the axon …

Spatiotemporal organization of exocytosis emerges during neuronal shape change

FL Urbina, SM Gomez, SL Gupton - Journal of Cell Biology, 2018 - rupress.org
Neurite elongation and branching in developing neurons requires plasmalemma expansion,
hypothesized to occur primarily via exocytosis. We posited that exocytosis in developing …

[PDF][PDF] TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

FL Urbina, S Menon, D Goldfarb, R Edwards, MB Major… - Cell reports, 2021 - cell.com
Neuronal morphogenesis involves dramatic plasma membrane expansion, fueled by
soluble N-ethylmaleimide-sensitive factor attachment protein eceptors (SNARE)-mediated …