[HTML][HTML] The postnatal GABA shift: a developmental perspective

C Peerboom, CJ Wierenga - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
GABA is the major inhibitory neurotransmitter that counterbalances excitation in the mature
brain. The inhibitory action of GABA relies on the inflow of chloride ions (Cl − ), which …

[HTML][HTML] Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia

…, J Wood, R Wang, CM Hall, C Peerboom… - Molecular …, 2021 - Springer
Background Microglia are active modulators of Alzheimer’s disease but their role in relation
to amyloid plaques and synaptic changes due to rising amyloid beta is unclear. We add …

Delaying the GABA shift indirectly affects membrane properties in the developing hippocampus

C Peerboom, S de Kater, N Jonker… - Journal of …, 2023 - Soc Neuroscience
During the first two postnatal weeks, intraneuronal chloride concentrations in rodents
gradually decrease, causing a shift from depolarizing to hyperpolarizing GABA responses. The …

Using SuperClomeleon to measure changes in intracellular chloride during development and after early life stress

LJ Herstel, C Peerboom, S Uijtewaal, D Selemangel… - eneuro, 2022 - eneuro.org
Intraneuronal chloride concentrations ([Cl − ] i ) decrease during development resulting in a
shift from depolarizing to hyperpolarizing GABA responses via chloride-permeable GABA A …

[CITATION][C] Need for negativity: The role of chloride homeostasis and the GABA shift in brain development

CNE Peerboom - 2023 - Universiteit Utrecht

[PDF][PDF] Een flexibel brein dankzij inhibitoire synapsen

CJ Wierenga - 2024 - repository.ubn.ru.nl
Carlijn Peerboom heeft hier belangrijke eerste stappen gezet 14 en Sam de Kater gaat
onder andere onderzoeken hoe het komt dat storingen in de hersenontwikkeling vaker …

Assessment of microglia influence in synaptic transmission and early amyloid-β plaque deposition in knock-in mouse models for Alzheimers disease

DP Benitez Jimenez - 2021 - discovery.ucl.ac.uk
… : Carlijn, Chloe, Katie, Kari, Rui, Natalie, Mila and Tashu, it was always a pleasure to work with
you in the lab and office every day. Katie, Kari and Carlijn: … MSc student Carlijn Peerboom. …

Sequential interplay of nicotinic and GABAergic signaling guides neuronal development

Z Liu, RA Neff, DK Berg - science, 2006 - science.org
GABA (γ-aminobutyric acid), the major inhibitory transmitter in the brain, goes through a
transitory phase of excitation during development. The excitatory phase promotes neuronal …