User profiles for C. Andrew Frank
C. Andrew FrankThe University of Iowa Carver College of Medicine and the Iowa Neuroscience Institute Verified email at uiowa.edu Cited by 1522 |
[HTML][HTML] Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis
CA Frank, MJ Kennedy, CP Goold, KW Marek… - Neuron, 2006 - cell.com
Homeostatic signaling systems are thought to interface with the mechanisms of neural plasticity
to achieve stable yet flexible neural circuitry. However, the time course, molecular design…
to achieve stable yet flexible neural circuitry. However, the time course, molecular design…
[PDF][PDF] A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2. 1 calcium channels
The molecular mechanisms underlying the homeostatic modulation of presynaptic
neurotransmitter release remain largely unknown. In a screen, we isolated mutations in Drosophila …
neurotransmitter release remain largely unknown. In a screen, we isolated mutations in Drosophila …
Homeostatic plasticity at the Drosophila neuromuscular junction
CA Frank - Neuropharmacology, 2014 - Elsevier
In biology, homeostasis refers to how cells maintain appropriate levels of activity. This concept
underlies a balancing act in the nervous system. Synapses require flexibility (ie plasticity) …
underlies a balancing act in the nervous system. Synapses require flexibility (ie plasticity) …
[PDF][PDF] Hierarchical microtubule organization controls axon caliber and transport and determines synaptic structure and stability
… C terminus might directly associate with MTs. Indeed, a His-tagged fusion protein of the first
part of the C … -terminal fusion protein, demonstrating that the C terminus binds to MTs in vitro (…
part of the C … -terminal fusion protein, demonstrating that the C terminus binds to MTs in vitro (…
Homeostatic control of Drosophila neuromuscular junction function
The ability to adapt to changing internal and external conditions is a key feature of biological
systems. Homeostasis refers to a regulatory process that stabilizes dynamic systems to …
systems. Homeostasis refers to a regulatory process that stabilizes dynamic systems to …
The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions
S Cordes, CA Frank, G Garriga - 2006 - journals.biologists.com
In the nematode Caenorhabditis elegans, neurons are generated from asymmetric divisions
in which a mother cell divides to produce daughters that differ in fate. Here, we demonstrate …
in which a mother cell divides to produce daughters that differ in fate. Here, we demonstrate …
HLH-14 is a C. elegans Achaete-Scute protein that promotes neurogenesis through asymmetric cell division
CA Frank, PD Baum, G Garriga - 2003 - journals.biologists.com
Achaete-Scute basic helix-loop-helix (bHLH) proteins promote neurogenesis during metazoan
development. In this study, we characterize a C. elegans Achaete-Scute homolog, HLH-…
development. In this study, we characterize a C. elegans Achaete-Scute homolog, HLH-…
[HTML][HTML] How voltage-gated calcium channels gate forms of homeostatic synaptic plasticity
CA Frank - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Throughout life, animals face a variety of challenges such as developmental growth, the
presence of toxins, or changes in temperature. Neuronal circuits and synapses respond to …
presence of toxins, or changes in temperature. Neuronal circuits and synapses respond to …
[HTML][HTML] A single-cross, RNA interference-based genetic tool for examining the long-term maintenance of homeostatic plasticity
DJ Brusich, AM Spring, CA Frank - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Homeostatic synaptic plasticity (HSP) helps neurons and synapses maintain physiologically
appropriate levels of output. The fruit fly Drosophila melanogaster larval neuromuscular …
appropriate levels of output. The fruit fly Drosophila melanogaster larval neuromuscular …
The Caenorhabditis elegans gene ham-2 links Hox patterning to migration of the HSN motor neuron
PD Baum, C Guenther, CA Frank, BV Pham… - Genes & …, 1999 - genesdev.cshlp.org
The Caenorhabditis elegans HSN motor neurons permit genetic analysis of neuronal
development at single-cell resolution. Theegl-5 Hox gene, which patterns the posterior of the …
development at single-cell resolution. Theegl-5 Hox gene, which patterns the posterior of the …