The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs)

D Perez-Madrigal, KG Finegan, B Paramo, C Tournier - Cellular signalling, 2012 - Elsevier
Activation of the extracellular-regulated protein kinase 5 (ERK5) has been associated with
mitogenic signal transduction. However, conflicting findings have challenged the idea that …

Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of …

…, T Montiel, B Páramo… - … of Neuropathology & …, 2011 - academic.oup.com
Prolonged activation of glutamate receptors leads to excitotoxicity. Several processes such
as reactive oxygen species (ROS) production and activation of the calcium-dependent …

[HTML][HTML] An essential role for neuregulin-4 in the growth and elaboration of developing neocortical pyramidal dendrites

B Paramo, S Wyatt, AM Davies - Experimental neurology, 2018 - Elsevier
Neuregulins, with the exception of neuregulin-4 (NRG4), have been shown to be extensively
involved in many aspects of neural development and function and are implicated in several …

Calpain activation induced by glucose deprivation is mediated by oxidative stress and contributes to neuronal damage

B Páramo, T Montiel, DR Hernández-Espinosa… - The international journal …, 2013 - Elsevier
The mechanisms leading to neuronal death during glucose deprivation have not been fully
elucidated, but a role of oxidative stress has been suggested. In the present study we have …

Neuregulin-4 is required for the growth and elaboration of striatal medium spiny neuron dendrites

B Paramo, S Wyatt, AM Davies - Journal of Neuropathology & …, 2019 - academic.oup.com
Medium spiny neurons (MSNs) comprise the vast majority of neurons in the striatum.
Changes in the exuberant dendrites of these widely connected neurons are associated with a …

Neuregulin-4 is required for maintaining soma size of pyramidal neurons in the motor cortex

B Paramo, SO Bachmann, SJ Baudouin… - Eneuro, 2021 - eneuro.org
The regulation of neuronal soma size is essential for appropriate brain circuit function and
its dysregulation is associated with several neurodevelopmental disorders. A defect in the …

The role of Sin1 in cell survival

B Paramo - 2015 - search.proquest.com
Cancer and neurodegeneration are detrimental conditions associated with an inappropriate
regulation of cell survival and cell death, causing compromised cells to evade death or …

Ecological research in the tropical alpine ecosystems of the Venezuelan páramo: past, present and future

LD Llambí, F Rada - Plant Ecology & Diversity, 2019 - Taylor & Francis
páramo regions have been studied, long-term ecological research efforts have concentrated
in sites within the largest, central páramo … National Park; Piedras Blancas and El Banco in …

The role of Sin1 in cell survival

BE Paramo Sanchez - 2015 - escholar.manchester.ac.uk
Cancer and neurodegeneration are detrimental conditions associated with an inappropriate
regulation of cell survival and cell death, causing compromised cells to evade death or …

The role of capacitance in the water balance of Andean giant rosette species

G Goldstein, F Meinzer… - Plant, Cell & …, 1984 - Wiley Online Library
… in the Piedras Blancas paramo, it was studied only in the Mucubaji paramo where it is the
dominant caulescent rosette species. In Piedras Blancas, the driest and highest paramo (0852'…