The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs)
D Perez-Madrigal, KG Finegan, B Paramo, C Tournier - Cellular signalling, 2012 - Elsevier
Activation of the extracellular-regulated protein kinase 5 (ERK5) has been associated with
mitogenic signal transduction. However, conflicting findings have challenged the idea that …
mitogenic signal transduction. However, conflicting findings have challenged the idea that …
Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of …
…, T Montiel, B Páramo… - … of Neuropathology & …, 2011 - academic.oup.com
Prolonged activation of glutamate receptors leads to excitotoxicity. Several processes such
as reactive oxygen species (ROS) production and activation of the calcium-dependent …
as reactive oxygen species (ROS) production and activation of the calcium-dependent …
[HTML][HTML] An essential role for neuregulin-4 in the growth and elaboration of developing neocortical pyramidal dendrites
B Paramo, S Wyatt, AM Davies - Experimental neurology, 2018 - Elsevier
Neuregulins, with the exception of neuregulin-4 (NRG4), have been shown to be extensively
involved in many aspects of neural development and function and are implicated in several …
involved in many aspects of neural development and function and are implicated in several …
Calpain activation induced by glucose deprivation is mediated by oxidative stress and contributes to neuronal damage
B Páramo, T Montiel, DR Hernández-Espinosa… - The international journal …, 2013 - Elsevier
The mechanisms leading to neuronal death during glucose deprivation have not been fully
elucidated, but a role of oxidative stress has been suggested. In the present study we have …
elucidated, but a role of oxidative stress has been suggested. In the present study we have …
Neuregulin-4 is required for the growth and elaboration of striatal medium spiny neuron dendrites
B Paramo, S Wyatt, AM Davies - Journal of Neuropathology & …, 2019 - academic.oup.com
Medium spiny neurons (MSNs) comprise the vast majority of neurons in the striatum.
Changes in the exuberant dendrites of these widely connected neurons are associated with a …
Changes in the exuberant dendrites of these widely connected neurons are associated with a …
Neuregulin-4 is required for maintaining soma size of pyramidal neurons in the motor cortex
B Paramo, SO Bachmann, SJ Baudouin… - Eneuro, 2021 - eneuro.org
The regulation of neuronal soma size is essential for appropriate brain circuit function and
its dysregulation is associated with several neurodevelopmental disorders. A defect in the …
its dysregulation is associated with several neurodevelopmental disorders. A defect in the …
The role of Sin1 in cell survival
B Paramo - 2015 - search.proquest.com
Cancer and neurodegeneration are detrimental conditions associated with an inappropriate
regulation of cell survival and cell death, causing compromised cells to evade death or …
regulation of cell survival and cell death, causing compromised cells to evade death or …
Ecological research in the tropical alpine ecosystems of the Venezuelan páramo: past, present and future
… páramo regions have been studied, long-term ecological research efforts have concentrated
in sites within the largest, central páramo … National Park; Piedras Blancas and El Banco in …
in sites within the largest, central páramo … National Park; Piedras Blancas and El Banco in …
The role of Sin1 in cell survival
BE Paramo Sanchez - 2015 - escholar.manchester.ac.uk
Cancer and neurodegeneration are detrimental conditions associated with an inappropriate
regulation of cell survival and cell death, causing compromised cells to evade death or …
regulation of cell survival and cell death, causing compromised cells to evade death or …
The role of capacitance in the water balance of Andean giant rosette species
G Goldstein, F Meinzer… - Plant, Cell & …, 1984 - Wiley Online Library
… in the Piedras Blancas paramo, it was studied only in the Mucubaji paramo where it is the
dominant caulescent rosette species. In Piedras Blancas, the driest and highest paramo (0852'…
dominant caulescent rosette species. In Piedras Blancas, the driest and highest paramo (0852'…