Early life experiences are crucial factors that shape brain development and function due to
their ability to induce structural and functional plasticity. Among these experiences, early‐life …

In the CA1 area of rat hippocampal slices, a combined application of 5-CT, a potent 5-HT 1A
and 5-HT 7 receptor agonist, and WAY 100635, a selective 5-HT 1A receptor antagonist, …

Initial observations in humans indicated that colostrinin, a complex of polypeptides derived
from the colostrum of sheep, facilitates cognitive functioning in patients with Alzheimer's …

To date, neurons have been the primary focus of research on the role of glucocorticoids in
the regulation of brain function and pathological behaviors, such as addiction. Astrocytes, …

In the search for new options for the pharmacological treatment of major depressive disorder,
compounds with a rapid onset of action and high efficacy but lacking a psychotomimetic …

The role that thyroid hormone deficiency plays in depression and synaptic plasticity in adults
has only begun to be elucidated. This paper analyzes the possible link between depression …

The data concerning antipsychotic-like activity of negative allosteric modulators (NAMs)/antagonists
of mGlu 7 receptors are limited. The only available ligands for this receptor are …

Our earlier study demonstrated, that antidepressant-like and also cognitive action of MTEP,
a metabotropic glutamate receptor subtype 5 (mGluR5) antagonist, was influenced by …

The effects of prenatal stress procedure were investigated in 3 months old male rats.
Prenatally stressed rats showed depressive-like behavior in the forced swim test, including …

Plasticity of the brain’s dopamine system plays a crucial role in adaptive behavior by
regulating appetitive motivation and the control of reinforcement learning. In this study, we …