User profiles for Astrid Prinz
Astrid PrinzAssociate Professor of Biology, Emory University Verified email at emory.edu Cited by 4299 |
Similar network activity from disparate circuit parameters
It is often assumed that cellular and synaptic properties need to be regulated to specific
values to allow a neuronal network to function properly. To determine how tightly neuronal …
values to allow a neuronal network to function properly. To determine how tightly neuronal …
Alternative to hand-tuning conductance-based models: construction and analysis of databases of model neurons
AA Prinz, CP Billimoria… - Journal of …, 2003 - journals.physiology.org
Conventionally, the parameters of neuronal models are hand-tuned using trial-and-error
searches to produce a desired behavior. Here, we present an alternative approach. We have …
searches to produce a desired behavior. Here, we present an alternative approach. We have …
The dynamic clamp comes of age
The dynamic clamp uses computer simulation to introduce artificial membrane or synaptic
conductances into biological neurons and to create hybrid circuits of real and model neurons. …
conductances into biological neurons and to create hybrid circuits of real and model neurons. …
Modeling stability in neuron and network function: the role of activity in homeostasis
Individual neurons display characteristic firing patterns determined by the number and kind
of ion channels in their membranes. We describe experimental and computational studies …
of ion channels in their membranes. We describe experimental and computational studies …
Animal-to-animal variability in motor pattern production in adults and during growth
Which features of network output are well preserved during growth of the nervous system and
across different preparations of the same size? To address this issue, we characterized the …
across different preparations of the same size? To address this issue, we characterized the …
[BOOK][B] Phase response curves in neuroscience: theory, experiment, and analysis
This book will track advances in the application of phase response (PR) analysis to the study
of electrically excitable cells, focusing on applications of PR analysis in the computational …
of electrically excitable cells, focusing on applications of PR analysis in the computational …
The functional consequences of changes in the strength and duration of synaptic inputs to oscillatory neurons
We studied the effect of synaptic inputs of different amplitude and duration on neural oscillators
by simulating synaptic conductance pulses in a bursting conductance-based pacemaker …
by simulating synaptic conductance pulses in a bursting conductance-based pacemaker …
Structure and visualization of high-dimensional conductance spaces
Neurons, and realistic models of neurons, typically express several different types of voltage-gated
conductances. These conductances are subject to continual regulation. Therefore it is …
conductances. These conductances are subject to continual regulation. Therefore it is …
On the role of theory and modeling in neuroscience
In recent years, the field of neuroscience has gone through rapid experimental advances
and a significant increase in the use of quantitative and computational methods. This growth …
and a significant increase in the use of quantitative and computational methods. This growth …
[PDF][PDF] Current compensation in neuronal homeostasis
… satory linkage will tend to stabilize the motor patterns son et al., 1993; Marder and Prinz,
2002; … Eve Marder and Astrid A. Prinz showed that expression of an inactive form of IA also …
2002; … Eve Marder and Astrid A. Prinz showed that expression of an inactive form of IA also …