User profiles for Archana Shankar

Archana Shankar

Stanford University
Verified email at stanford.edu
Cited by 580

Context-dependent functional compensation between Ythdf m6A reader proteins

…, M Zerbib, I Kilimnik, S Aigner, A Shankar… - Genes & …, 2020 - genesdev.cshlp.org
The N6-methyladenosine (m 6 A) modification is the most prevalent post-transcriptional
mRNA modification, regulating mRNA decay and splicing. It plays a major role during normal …

[HTML][HTML] Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

…, BA Yee, H Li, AA Madrigal, NJ Neill, A Shankar… - Molecular cell, 2021 - cell.com
RNA-binding proteins (RBPs) are critical regulators of post-transcriptional gene expression,
and aberrant RBP-RNA interactions can promote cancer progression. Here, we interrogate …

[HTML][HTML] Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

…, SS Park, AB Kamstrup, AM Rasmussen, A Shankar… - Genome medicine, 2020 - Springer
Background Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts
with potential to modulate other regulatory RNAs. A few circRNAs have been shown to bind …

Large-scale tethered function assays identify factors that regulate mRNA stability and translation

…, FE Tan, JL Schwartz, JC Schmok, A Shankar… - Nature structural & …, 2020 - nature.com
The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear,
highlighting a major bottleneck to a full understanding of gene expression regulation. Here, we …

“Females are not just 'protected'males”: Sex-specific vulnerabilities in placenta and brain after prenatal immune disruption

…, AR Narayan, ML Kielhold, HM Moon, A Shankar… - eneuro, 2019 - eneuro.org
Current perceptions of genetic and environmental vulnerabilities in the developing fetus are
biased toward male outcomes. An argument is made that males are more vulnerable to …

Modulation of IL-4/IL-13 cytokine signaling in the context of allergic disease

A Shankar, JW McAlees, IP Lewkowich - Journal of Allergy and Clinical …, 2022 - Elsevier
Aberrant activation of CD4 T H 2 cells and excessive production of T H 2 cytokines such as
IL-4 and IL-13 have been implicated in the pathogenesis of allergic diseases. Generally, IL-4 …

MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy

…, T Bridges, JR Mueller, A Shankar… - Science translational …, 2022 - science.org
Myotonic dystrophy type 1 (DM1) is a multisystem, autosomal-dominant inherited disorder
caused by CTG microsatellite repeat expansions (MREs) in the 3′ untranslated region of the …

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis

…, EM McNally, JEM Fox, H Hong, A Shankar… - Genes & …, 2020 - genesdev.cshlp.org
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates
physiology and behavior through molecular programs that remain incompletely understood. …

Incidence of multiple bacterial infections in Pacific whiteleg shrimp, Litopenaeus vannamei

…, A Gopalakrishnan, A Shankar… - Aquaculture …, 2022 - Wiley Online Library
A rare incidence of multiple bacterial infections was reported in Litopenaeus vannamei grow‐out
ponds in India. The pathogenic organisms identified are Aeromonas veronii, Bacillus …

Interpreting the Narratives of Non-Traditional Students: An Exploratory Study.

AD Shankar - 1994 - ERIC
A study investigated the communication and learning problems of nontraditional students.
Its methodology drew on case studies and interviews with 10 nontraditional students at two …