User profiles for Anthony J. Baucum

AJ Baucum

Assitant Professor, IUPUI
Verified email at iupui.edu
Cited by 1490

[HTML][HTML] Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalis

TL Kash, AJ Baucum, KL Conrad, RJ Colbran… - …, 2009 - nature.com
Chronic alcohol exposure can cause dramatic behavioral alterations, including increased
anxiety-like behavior and depression. These alterations are proposed to be due in part to …

GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis

…, JR Klug, Y Silberman, AJ Baucum… - Proceedings of the …, 2012 - National Acad Sciences
The bed nucleus of the stria terminalis (BNST) is a critical region for alcohol/drug-induced
negative affect and stress-induced reinstatement. NMDA receptor (NMDAR)-dependent …

CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling

…, TS Ramikie, VS Cavener, T Rentz, AJ Baucum… - Nature …, 2013 - nature.com
The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates activity-dependent depression
of excitatory neurotransmission at central synapses, but the molecular regulation of 2-AG …

Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain

AJ Baucum, BC Shonesy, KL Rose… - ACS chemical …, 2015 - ACS Publications
Ca 2+ /calmodulin-dependent protein kinase IIα (CaMKIIα) autophosphorylation at Thr286
and Thr305/Thr306 regulates kinase activity and modulates subcellular targeting and is …

Prenatal methadone exposure disrupts behavioral development and alters motor neuron intrinsic properties and local circuitry

…, EA Newell, EA Engleman, AJ Baucum, J Kim… - Elife, 2021 - elifesciences.org
Despite the rising prevalence of methadone treatment in pregnant women with opioid use
disorder, the effects of methadone on neurobehavioral development remain unclear. We …

Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine-and hyperthermia-associated mechanism

AJ Baucum, KS Rau, EL Riddle… - Journal of …, 2004 - Soc Neuroscience
Multiple high-dose administrations of methamphetamine (METH) both rapidly (within hours)
decrease plasmalemmal dopamine (DA) uptake and cause long-term deficits in DA …

[PDF][PDF] Astrocytes regulate the development and maturation of retinal ganglion cells derived from human pluripotent stem cells

…, A Sridhar, CM Fligor, EM Feder, MC Edler, AJ Baucum… - Stem cell reports, 2019 - cell.com
Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this
connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated …

[HTML][HTML] Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and …

YA Nikandrova, Y Jiao, AJ Baucum, SJ Tavalin… - Journal of biological …, 2010 - ASBMB
Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) promotes trafficking and activation
of the GluR1 subunit of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic acid-type …

[HTML][HTML] CaMKII enhances voltage-gated sodium channel Nav1. 6 activity and neuronal excitability

AS Zybura, AJ Baucum, AM Rush, TR Cummins… - Journal of Biological …, 2020 - ASBMB
Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature axon initial
segments and nodes, making it critical for initiation and propagation of neuronal impulses. …

[HTML][HTML] Substrate-selective and calcium-independent activation of CaMKII by α-actinin

N Jalan-Sakrikar, RK Bartlett, AJ Baucum… - Journal of Biological …, 2012 - ASBMB
Protein-protein interactions are thought to modulate the efficiency and specificity of Ca 2+ /calmodulin
(CaM)-dependent protein kinase II (CaMKII) signaling in specific subcellular …