User profiles for Anthony J. Baucum
AJ BaucumAssitant Professor, IUPUI Verified email at iupui.edu Cited by 1490 |
[HTML][HTML] Alcohol exposure alters NMDAR function in the bed nucleus of the stria terminalis
Chronic alcohol exposure can cause dramatic behavioral alterations, including increased
anxiety-like behavior and depression. These alterations are proposed to be due in part to …
anxiety-like behavior and depression. These alterations are proposed to be due in part to …
GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis
…, JR Klug, Y Silberman, AJ Baucum… - Proceedings of the …, 2012 - National Acad Sciences
The bed nucleus of the stria terminalis (BNST) is a critical region for alcohol/drug-induced
negative affect and stress-induced reinstatement. NMDA receptor (NMDAR)-dependent …
negative affect and stress-induced reinstatement. NMDA receptor (NMDAR)-dependent …
CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling
…, TS Ramikie, VS Cavener, T Rentz, AJ Baucum… - Nature …, 2013 - nature.com
The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates activity-dependent depression
of excitatory neurotransmission at central synapses, but the molecular regulation of 2-AG …
of excitatory neurotransmission at central synapses, but the molecular regulation of 2-AG …
Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain
AJ Baucum, BC Shonesy, KL Rose… - ACS chemical …, 2015 - ACS Publications
Ca 2+ /calmodulin-dependent protein kinase IIα (CaMKIIα) autophosphorylation at Thr286
and Thr305/Thr306 regulates kinase activity and modulates subcellular targeting and is …
and Thr305/Thr306 regulates kinase activity and modulates subcellular targeting and is …
Prenatal methadone exposure disrupts behavioral development and alters motor neuron intrinsic properties and local circuitry
…, EA Newell, EA Engleman, AJ Baucum, J Kim… - Elife, 2021 - elifesciences.org
Despite the rising prevalence of methadone treatment in pregnant women with opioid use
disorder, the effects of methadone on neurobehavioral development remain unclear. We …
disorder, the effects of methadone on neurobehavioral development remain unclear. We …
Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine-and hyperthermia-associated mechanism
AJ Baucum, KS Rau, EL Riddle… - Journal of …, 2004 - Soc Neuroscience
Multiple high-dose administrations of methamphetamine (METH) both rapidly (within hours)
decrease plasmalemmal dopamine (DA) uptake and cause long-term deficits in DA …
decrease plasmalemmal dopamine (DA) uptake and cause long-term deficits in DA …
[PDF][PDF] Astrocytes regulate the development and maturation of retinal ganglion cells derived from human pluripotent stem cells
Retinal ganglion cells (RGCs) form the connection between the eye and the brain, with this
connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated …
connectivity disrupted in numerous blinding disorders. Previous studies have demonstrated …
[HTML][HTML] Ca2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and …
Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) promotes trafficking and activation
of the GluR1 subunit of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic acid-type …
of the GluR1 subunit of α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic acid-type …
[HTML][HTML] CaMKII enhances voltage-gated sodium channel Nav1. 6 activity and neuronal excitability
AS Zybura, AJ Baucum, AM Rush, TR Cummins… - Journal of Biological …, 2020 - ASBMB
Nav1.6 is the primary voltage-gated sodium channel isoform expressed in mature axon initial
segments and nodes, making it critical for initiation and propagation of neuronal impulses. …
segments and nodes, making it critical for initiation and propagation of neuronal impulses. …
[HTML][HTML] Substrate-selective and calcium-independent activation of CaMKII by α-actinin
N Jalan-Sakrikar, RK Bartlett, AJ Baucum… - Journal of Biological …, 2012 - ASBMB
Protein-protein interactions are thought to modulate the efficiency and specificity of Ca 2+ /calmodulin
(CaM)-dependent protein kinase II (CaMKII) signaling in specific subcellular …
(CaM)-dependent protein kinase II (CaMKII) signaling in specific subcellular …