Moderate-intensity endurance-exercise training in patients with sickle-cell disease without severe chronic complications (EXDRE): an open-label randomised …
…, F Galactéros, E Audureau, AN Merlet… - The Lancet …, 2018 - thelancet.com
Background Exercise could be a triggering factor for vaso-occlusive crises in patients with
sickle-cell disease. We aimed to investigate whether a patient-adapted training programme of …
sickle-cell disease. We aimed to investigate whether a patient-adapted training programme of …
Beneficial effects of endurance exercise training on skeletal muscle microvasculature in sickle cell disease patients
AN Merlet, LA Messonnier… - Blood, The Journal …, 2019 - ashpublications.org
Sickle cell disease (SCD) is a genetic hemoglobinopathy leading to 2 major clinical
manifestations: severe chronic hemolytic anemia and iterative vaso-occlusive crises. SCD is also …
manifestations: severe chronic hemolytic anemia and iterative vaso-occlusive crises. SCD is also …
[HTML][HTML] A sensory signal related to left-right symmetry modulates intra-and interlimb cutaneous reflexes during locomotion in intact cats
S Mari, CG Lecomte, AN Merlet, J Audet… - Frontiers in systems …, 2023 - frontiersin.org
During locomotion, cutaneous reflexes play an essential role in rapidly responding to an
external perturbation, for example to prevent a fall when the foot contacts an obstacle. In cats …
external perturbation, for example to prevent a fall when the foot contacts an obstacle. In cats …
Neuromechanical strategies for obstacle negotiation during overground locomotion following incomplete spinal cord injury in adult cats
…, S Mari, J Audet, S Yassine, AN Merlet… - Journal of …, 2023 - Soc Neuroscience
Following incomplete spinal cord injury in animals, including humans, substantial locomotor
recovery can occur. However, functional aspects of locomotion, such as negotiating …
recovery can occur. However, functional aspects of locomotion, such as negotiating …
Spinal sensorimotor circuits play a prominent role in hindlimb locomotor recovery after staggered thoracic lateral hemisections but cannot restore posture and interlimb …
…, CG Lecomte, S Mari, F Soucy, C Morency, AN Merlet… - Eneuro, 2023 - eneuro.org
Spinal sensorimotor circuits interact with supraspinal and peripheral inputs to generate
quadrupedal locomotion. Ascending and descending spinal pathways ensure coordination …
quadrupedal locomotion. Ascending and descending spinal pathways ensure coordination …
Modulation of the gait pattern during split-belt locomotion after lateral spinal cord hemisection in adult cats
…, S Mari, J Audet, AN Merlet… - Journal of …, 2022 - journals.physiology.org
Most previous studies investigated the recovery of locomotion in animals and people with
incomplete spinal cord injury (SCI) during relatively simple tasks (eg, walking in a straight line …
incomplete spinal cord injury (SCI) during relatively simple tasks (eg, walking in a straight line …
[HTML][HTML] Inhibition and facilitation of the spinal locomotor central pattern generator and reflex circuits by somatosensory feedback from the lumbar and perineal regions …
AN Merlet, J Harnie, A Frigon - Frontiers in Neuroscience, 2021 - frontiersin.org
Somatosensory feedback from peripheral receptors dynamically interacts with networks located
in the spinal cord and brain to control mammalian locomotion. Although somatosensory …
in the spinal cord and brain to control mammalian locomotion. Although somatosensory …
Muscle structural, energetic and functional benefits of endurance exercise training in sickle cell disease
AN Merlet, L Féasson, P Bartolucci… - American journal of …, 2020 - Wiley Online Library
Sickle cell disease (SCD) patients display skeletal muscle hypotrophy, altered oxidative
capacity, exercise intolerance and poor quality of life. We previously demonstrated that moderate…
capacity, exercise intolerance and poor quality of life. We previously demonstrated that moderate…
[PDF][PDF] How sickle cell disease impairs skeletal muscle function: implications in daily life
AN Merlet, B Chatel, C Hourde… - Medicine & Science …, 2019 - researchgate.net
2019. Sickle cell disease (SCD) is the most frequent life-threatening genetic
hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS). …
hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS). …
[HTML][HTML] Effect of knee angle on neuromuscular assessment of plantar flexor muscles: A reliability study
AN Merlet, T Cattagni, C Cornu, M Jubeau - PLoS One, 2018 - journals.plos.org
Introduction This study aimed to determine the intra- and inter-session reliability of
neuromuscular assessment of plantar flexor (PF) muscles at three knee angles. Methods Twelve …
neuromuscular assessment of plantar flexor (PF) muscles at three knee angles. Methods Twelve …