User profiles for Ana Ligia Scott
 | Scott, Ana L, Scott AL., Ana Ligia Scott, Scott AL, AL Scott, Ana L ScottFull Professor at UFABC Verified email at ufabc.edu.br Cited by 677 |
[HTML][HTML] Towards gaining sight of multiscale events: utilizing network models and normal modes in hybrid methods
… 1 5 , Pemra Doruker 1 5 , Ana Ligia Scott 2 5 , David Perahia 3 , Ivet Bahar 1 … Ana Ligia
Scott: Formal analysis, Methodology, Visualization, Writing - original draft, … Perahia, LPB Scott …
Scott: Formal analysis, Methodology, Visualization, Writing - original draft, … Perahia, LPB Scott …
[HTML][HTML] Sampling of protein conformational space using hybrid simulations: A critical assessment of recent methods
Recent years have seen several hybrid simulation methods for exploring the conformational
space of proteins and their complexes or assemblies. These methods often combine fast …
space of proteins and their complexes or assemblies. These methods often combine fast …
[HTML][HTML] Structural dynamics of DPP-4 and its influence on the projection of bioactive ligands
Dipeptidyl peptidase-4 (DPP-4) is a target to treat type II diabetes mellitus. Therefore, it is
important to understand the structural aspects of this enzyme and its interaction with drug …
important to understand the structural aspects of this enzyme and its interaction with drug …
PINK1 interacts with VCP/p97 and activates PKA to promote NSFL1C/p47 phosphorylation and dendritic arborization in neurons
While PTEN-induced kinase 1 (PINK1) is well characterized for its role in mitochondrial
homeostasis, much less is known concerning its ability to prevent synaptodendritic degeneration. …
homeostasis, much less is known concerning its ability to prevent synaptodendritic degeneration. …
Interaction between 1-pyrenesulfonic acid and albumin: Moving inside the protein
Due to the high sensitivity to alterations in microenvironment polarity of macromolecules,
pyrene and its derivatives have long been applied in biosciences. Human serum albumin (HSA)…
pyrene and its derivatives have long been applied in biosciences. Human serum albumin (HSA)…
[HTML][HTML] Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor
The human cytomegalovirus (HCMV) UL111A gene encodes several homologs of the cellular
interleukin 10 (cIL-10). Alternative splicing in the UL111A region produces two relatively …
interleukin 10 (cIL-10). Alternative splicing in the UL111A region produces two relatively …
Predicting regions prone to protein aggregation based on SVM algorithm
The phenomenon of protein aggregation has been associated with several neurodegenerative
diseases, such as Parkinson's and Alzheimer's. Computational tools have been used to …
diseases, such as Parkinson's and Alzheimer's. Computational tools have been used to …
[HTML][HTML] Methyl divanillate: redox properties and binding affinity with albumin of an antioxidant and potential NADPH oxidase inhibitor
Vanillic acid is a widely used food additive (flavouring agent, JECFA number: 959) with
many reported beneficial biological effects. The same is true for its ester derivative (methyl …
many reported beneficial biological effects. The same is true for its ester derivative (methyl …
[HTML][HTML] Unveiling functional motions based on point mutations in biased signaling systems: A normal mode study on nerve growth factor bound to TrkA
Many receptors elicit signal transduction by activating multiple intracellular pathways. This
transduction can be triggered by a non-specific ligand, which simultaneously activates all the …
transduction can be triggered by a non-specific ligand, which simultaneously activates all the …
Virtual screening and in vitro assays of novel hits as promising DPP-4 inhibitors
Diabetes is a metabolic disorder that presents hyperglycemia and vascular complications
due to the non-production of insulin or its inappropriate use by the body. One of the strategies …
due to the non-production of insulin or its inappropriate use by the body. One of the strategies …