Mouse models of Alzheimer's disease
AM Hall, ED Roberson - Brain research bulletin, 2012 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
today. The search for new treatments is made ever more urgent by prospects for increasing …
today. The search for new treatments is made ever more urgent by prospects for increasing …
Tau-dependent Kv4. 2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease
AM Hall, BT Throesch, SC Buckingham… - Journal of …, 2015 - Soc Neuroscience
Neuronal hyperexcitability occurs early in the pathogenesis of Alzheimer's disease (AD)
and contributes to network dysfunction in AD patients. In other disorders with neuronal …
and contributes to network dysfunction in AD patients. In other disorders with neuronal …
The dendritic hypothesis for Alzheimer's disease pathophysiology
JN Cochran, AM Hall, ED Roberson - Brain research bulletin, 2014 - Elsevier
Converging evidence indicates that processes occurring in and around neuronal dendrites
are central to the pathogenesis of Alzheimer's disease. These data support the concept of a “…
are central to the pathogenesis of Alzheimer's disease. These data support the concept of a “…
[PDF][PDF] Dual and opposing roles of microRNA-124 in epilepsy are mediated through inflammatory and NRSF-dependent gene networks
…, D Dey, Y Chen, KP Patterson, EJ Magnetta, AM Hall… - Cell reports, 2016 - cell.com
Insult-provoked transformation of neuronal networks into epileptic ones involves multiple
mechanisms. Intervention studies have identified both dysregulated inflammatory pathways …
mechanisms. Intervention studies have identified both dysregulated inflammatory pathways …
Seizure resistance without parkinsonism in aged mice after tau reduction
Z Li, AM Hall, M Kelinske, ED Roberson - Neurobiology of aging, 2014 - Elsevier
… Author links open overlay panel Zhiyong Li a , Alicia M. Hall a , Mark Kelinske b , Erik D. …
For reporting purposes, 57 Fe 16 O (73 m/z) was chosen as the reportable mass. Before analysis…
For reporting purposes, 57 Fe 16 O (73 m/z) was chosen as the reportable mass. Before analysis…
Effect of Endogenous Androgens on 17β-Estradiol-Mediated Protection after Spinal Cord Injury in Male Rats
S Kachadroka, AM Hall, TL Niedzielko… - Journal of …, 2010 - liebertpub.com
Several groups have recently shown that 17β-estradiol is protective in spinal cord injury (SCI).
Testosterone can be aromatized to 17β-estradiol and may increase estrogen-mediated …
Testosterone can be aromatized to 17β-estradiol and may increase estrogen-mediated …
Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test
…, AJ Filiano, BA Warmus, AM Hall… - Genes, Brain and …, 2016 - Wiley Online Library
Loss‐of‐function mutations in progranulin ( GRN ) are a major autosomal dominant cause of
frontotemporal dementia ( FTD ), a neurodegenerative disorder in which social behavior is …
frontotemporal dementia ( FTD ), a neurodegenerative disorder in which social behavior is …
Dexamethasone attenuates hyperexcitability provoked by experimental febrile status epilepticus
The role of neuroinflammation in the mechanisms of epilepsy development is important
because inflammatory mediators provide tractable targets for intervention. Inflammation is …
because inflammatory mediators provide tractable targets for intervention. Inflammation is …
The role of Sirt1 in epileptogenesis
AM Hall, GP Brennan, TM Nguyen, A Singh-Taylor… - Eneuro, 2017 - eneuro.org
The mechanisms by which brain insults lead to subsequent epilepsy remain unclear. Insults,
including trauma, stroke, tumors, infections, and long seizures [status epilepticus (SE)], …
including trauma, stroke, tumors, infections, and long seizures [status epilepticus (SE)], …
Augmented seizure susceptibility and hippocampal epileptogenesis in a translational mouse model of febrile status epilepticus
KD Chen, AM Hall, MM Garcia‐Curran, GA Sanchez… - …, 2021 - Wiley Online Library
Objective Prolonged fever‐induced seizures (febrile status epilepticus [FSE]) during early
childhood increase the risk for later epilepsy, but the underlying mechanisms are incompletely …
childhood increase the risk for later epilepsy, but the underlying mechanisms are incompletely …