User profiles for Alain Chédotal
Alain ChedotalInstitut de la Vision, Paris Verified email at upmc.fr Cited by 19204 |
Tissue clearing and its applications in neuroscience
State-of-the-art tissue-clearing methods provide subcellular-level optical access to intact
tissues from individual organs and even to some entire mammals. When combined with light-…
tissues from individual organs and even to some entire mammals. When combined with light-…
Decoding human fetal liver haematopoiesis
…, P Carey, AC Villani, A Roy, A Regev, A Chédotal… - Nature, 2019 - nature.com
Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly defined in …
[PDF][PDF] Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III
Semaphorins are a large family of secreted and transmembrane proteins, several of which
are implicated in repulsive axon guidance. Neuropilin (neuropilin-1) was recently identified as …
are implicated in repulsive axon guidance. Neuropilin (neuropilin-1) was recently identified as …
[HTML][HTML] A roadmap for the human developmental cell atlas
The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human Cell Atlas,
aims to create a comprehensive reference map of cells during development. This will be …
aims to create a comprehensive reference map of cells during development. This will be …
[HTML][HTML] Single-cell roadmap of human gonadal development
…, E Prigmore, M Herbert, A Moffett, A Chédotal… - Nature, 2022 - nature.com
Gonadal development is a complex process that involves sex determination followed by
divergent maturation into either testes or ovaries 1 . Historically, limited tissue accessibility, a …
divergent maturation into either testes or ovaries 1 . Historically, limited tissue accessibility, a …
[PDF][PDF] Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance
V Castellani, A Chédotal, M Schachner… - Neuron, 2000 - cell.com
In humans, defects of the corticospinal tract have been attributed to mutations in the gene
encoding L1 CAM, a phenotype that is reproduced in L1-deficient mice. Using coculture assays…
encoding L1 CAM, a phenotype that is reproduced in L1-deficient mice. Using coculture assays…
[HTML][HTML] Neuropilin-2 regulates the development of select cranial and sensory nerves and hippocampal mossy fiber projections
Neuropilin-1 and neuropilin-2 bind differentially to different class 3 semaphorins and are
thought to provide the ligand-binding moieties in receptor complexes mediating repulsive …
thought to provide the ligand-binding moieties in receptor complexes mediating repulsive …
The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion
…, C Lubetzki, I Dusart, A Chédotal - Journal of …, 2003 - Soc Neuroscience
Semaphorins are a family of secreted and membrane-bound proteins, known to regulate
axonal pathfinding. Sema4D, also called CD100, was first isolated in the immune system where …
axonal pathfinding. Sema4D, also called CD100, was first isolated in the immune system where …
Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells
…, RJM Franklin, B Ji, Z Shao, A Chédotal… - Annals of Neurology …, 2009 - Wiley Online Library
Objective Repair of demyelinated axons in diseases such as multiple sclerosis requires
activation of the myelination program in existing or newly recruited oligodendrocyte precursor …
activation of the myelination program in existing or newly recruited oligodendrocyte precursor …
[HTML][HTML] Tridimensional visualization and analysis of early human development
Generating a precise cellular and molecular cartography of the human embryo is essential
to our understanding of the mechanisms of organogenesis in normal and pathological …
to our understanding of the mechanisms of organogenesis in normal and pathological …