Morphological and biochemical features of Borrelia burgdorferi pleomorphic forms
L Meriläinen, A Herranen, A Schwarzbach… - …, 2015 - microbiologyresearch.org
The spirochaete bacterium Borrelia burgdorferi sensu lato is the causative agent of Lyme
disease, the most common tick-borne infection in the northern hemisphere. There is a long-…
disease, the most common tick-borne infection in the northern hemisphere. There is a long-…
[HTML][HTML] Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
A Herranen, K Ikäheimo, T Lankinen, E Pakarinen… - Cell death & …, 2020 - nature.com
The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor
(MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis…
(MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis…
[HTML][HTML] Transient developmental exposure to low doses of bisphenol F negatively affects neurogliogenesis and olfactory behaviour in adult mice
Neural stem cells in the murine subventricular zone (SVZ) reactivate during postnatal development
to generate neurons and glia throughout adulthood. We previously demonstrated that …
to generate neurons and glia throughout adulthood. We previously demonstrated that …
[HTML][HTML] Pleomorphic forms of Borrelia burgdorferi induce distinct immune responses
L Meriläinen, H Brander, A Herranen… - Microbes and …, 2016 - Elsevier
Borrelia burgdorferi is the causative agent of tick-borne Lyme disease. As a response to
environmental stress B. burgdorferi can change its morphology to a round body form. The role of …
environmental stress B. burgdorferi can change its morphology to a round body form. The role of …
The stress response in the non-sensory cells of the cochlea under pathological conditions—possible role in mediating noise vulnerability
A Herranen, K Ikäheimo, J Virkkala… - Journal of the Association …, 2018 - Springer
Various stressors, such as loud sounds and the effects of aging, impair the function and
viability of the cochlear sensory cells, the hair cells. Stressors trigger pathophysiological …
viability of the cochlear sensory cells, the hair cells. Stressors trigger pathophysiological …
[HTML][HTML] 2, 4, 6-trinitrobenzene sulfonic acid-induced chronic colitis with fibrosis and modulation of TGF-β1 signaling
E Loeuillard, J Bertrand, A Herranen… - World journal of …, 2014 - ncbi.nlm.nih.gov
METHODS: Chronic colitis was induced in rats by repeated administration of increasing dose
of 2, 4, 6-trinitrobenzene sulfonic acid (TNBS, 15, 30, 45, 60, 60, 60 mg) by rectal injection …
of 2, 4, 6-trinitrobenzene sulfonic acid (TNBS, 15, 30, 45, 60, 60, 60 mg) by rectal injection …
c-Jun N-terminal phosphorylation: biomarker for cellular stress rather than cell death in the injured cochlea
T Anttonen, A Herranen, J Virkkala, A Kirjavainen… - Eneuro, 2016 - eneuro.org
Prevention of auditory hair cell death offers therapeutic potential to rescue hearing.
Pharmacological blockade of JNK/c-Jun signaling attenuates injury-induced hair cell loss, but with …
Pharmacological blockade of JNK/c-Jun signaling attenuates injury-induced hair cell loss, but with …
[HTML][HTML] Indispensable role of Mdm2/p53 interaction during the embryonic and postnatal inner ear development
M Laos, M Sulg, A Herranen, T Anttonen, U Pirvola - Scientific Reports, 2017 - nature.com
p53 is a key component of a signaling network that protects cells against various stresses.
As excess p53 is detrimental to cells, its levels are tightly controlled by several mechanisms. …
As excess p53 is detrimental to cells, its levels are tightly controlled by several mechanisms. …
Results and costs of intensive care in a tertiary university hospital from 1996–2000
I Parviainen, A Herranen, A Holm… - Acta …, 2004 - Wiley Online Library
Background: Costs of intensive care may be 20% of all hospital costs. Population aging likely
increases the demand for intensive care services, while health care has financial limitations…
increases the demand for intensive care services, while health care has financial limitations…
Desalting amino acid solutions by ion exchange
GC Mueller, G Bowman, A Herranen - Analytical Chemistry, 1955 - ACS Publications
The following materials are required for a single chamber. Five single-weight window panes
(12 X 24 X3a6 inch), 1443/8 inches of 1-inch white adhesive tape,*/s ounce of Seal All …
(12 X 24 X3a6 inch), 1443/8 inches of 1-inch white adhesive tape,*/s ounce of Seal All …