User profiles for A. V. Domingues
Ana Verónica DominguesPhD student in Health Sciences Verified email at alunos.uminho.pt Cited by 483 |
Glial cells in Parkinson´ s disease: protective or deleterious?
AV Domingues, IM Pereira, H Vilaça-Faria… - Cellular and Molecular …, 2020 - Springer
Glial cells have been identified more than 100 years ago, and are known to play a key role
in the central nervous system (CNS) function. A recent piece of evidence is emerging …
in the central nervous system (CNS) function. A recent piece of evidence is emerging …
[HTML][HTML] Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion
Deficits in decoding rewarding (and aversive) signals are present in several neuropsychiatric
conditions such as depression and addiction, emphasising the importance of studying the …
conditions such as depression and addiction, emphasising the importance of studying the …
[HTML][HTML] Mild prenatal stress causes emotional and brain structural modifications in rats of both sexes
…, B Coimbra, S Borges, AV Domingues… - Frontiers in behavioral …, 2018 - frontiersin.org
Stress or high levels of glucocorticoids (GCs) during developmental periods is known to
induce persistent effects in the neuroendocrine circuits that control stress response, which may …
induce persistent effects in the neuroendocrine circuits that control stress response, which may …
Nucleus accumbens microcircuit underlying D2-MSN-driven increase in motivation
The nucleus accumbens (NAc) plays a central role in reinforcement and motivation. Around
95% of the NAc neurons are medium spiny neurons (MSNs), divided into those expressing …
95% of the NAc neurons are medium spiny neurons (MSNs), divided into those expressing …
[PDF][PDF] Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior
C Soares-Cunha, AV Domingues, R Correia… - Cell Reports, 2022 - cell.com
The nucleus accumbens (NAc) is a key region in motivated behaviors. NAc medium spiny
neurons (MSNs) are divided into those expressing dopamine receptor D1 or D2. Classically, …
neurons (MSNs) are divided into those expressing dopamine receptor D1 or D2. Classically, …
[HTML][HTML] Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia
R Gaspar, C Soares-Cunha, AV Domingues… - Neurobiology of …, 2021 - Elsevier
Prenatal exposure to stress or glucocorticoids (GC) is associated with the appearance of
psychiatric diseases later in life. Microglia, the immune cells of the brain, are altered in stress-…
psychiatric diseases later in life. Microglia, the immune cells of the brain, are altered in stress-…
[HTML][HTML] Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
…, NAP Vasconcelos, AV Domingues… - Nature …, 2019 - nature.com
The laterodorsal tegmentum (LDT) is associated with reward considering that it modulates
VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly …
VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly …
[HTML][HTML] Impact of aging on the 6-OHDA-induced rat model of Parkinson's disease
…, B Mendes-Pinheiro, AV Domingues… - International journal of …, 2020 - mdpi.com
Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder.
The neurodegeneration leading to incapacitating motor abnormalities mainly occurs in …
The neurodegeneration leading to incapacitating motor abnormalities mainly occurs in …
[HTML][HTML] Preclinical comparison of stem cells secretome and levodopa application in a 6-hydroxydopamine rat model of Parkinson's disease
Parkinson’s Disease (PD) is characterized by the massive loss of dopaminergic neurons,
leading to the appearance of several motor impairments. Current pharmacological treatments, …
leading to the appearance of several motor impairments. Current pharmacological treatments, …
[HTML][HTML] The duration of stress determines sex specificities in the vulnerability to depression and in the morphologic remodeling of neurons and microglia
R Gaspar, C Soares-Cunha, AV Domingues… - Frontiers in Behavioral …, 2022 - frontiersin.org
Stress exposure has been shown to induce a variety of molecular and functional alterations
associated with anxiety and depression. Some studies suggest that microglia, the immune …
associated with anxiety and depression. Some studies suggest that microglia, the immune …