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mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory.
Sharma V, Oliveira MM, Sood R, Khlaifia A, Lou D, Hooshmandi M, Hung TY, Mahmood N, Reeves M, Ho-Tieng D, Cohen N, Cheng PC, Rahim MMA, Prager-Khoutorsky M, Kaufman RJ, Rosenblum K, Lacaille JC, Khoutorsky A, Klann E, Sonenberg N. Sharma V, et al. Among authors: khlaifia a. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2308671120. doi: 10.1073/pnas.2308671120. Epub 2023 Nov 28. Proc Natl Acad Sci U S A. 2023. PMID: 38015848
Antidepressant actions of ketamine engage cell-specific translation via eIF4E.
Aguilar-Valles A, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Khlaifia A, Skaleka A, Lopez-Canul M, Torres-Berrio A, Bermudez S, Rurak GM, Simard S, Salmaso N, Gobbi G, Lacaille JC, Sonenberg N. Aguilar-Valles A, et al. Among authors: khlaifia a. Nature. 2021 Feb;590(7845):315-319. doi: 10.1038/s41586-020-03047-0. Epub 2020 Dec 16. Nature. 2021. PMID: 33328636
eIF2α controls memory consolidation via excitatory and somatostatin neurons.
Sharma V, Sood R, Khlaifia A, Eslamizade MJ, Hung TY, Lou D, Asgarihafshejani A, Lalzar M, Kiniry SJ, Stokes MP, Cohen N, Nelson AJ, Abell K, Possemato AP, Gal-Ben-Ari S, Truong VT, Wang P, Yiannakas A, Saffarzadeh F, Cuello AC, Nader K, Kaufman RJ, Costa-Mattioli M, Baranov PV, Quintana A, Sanz E, Khoutorsky A, Lacaille JC, Rosenblum K, Sonenberg N. Sharma V, et al. Among authors: khlaifia a. Nature. 2020 Oct;586(7829):412-416. doi: 10.1038/s41586-020-2805-8. Epub 2020 Oct 7. Nature. 2020. PMID: 33029011 Free PMC article.
Regulation of Hippocampal Memory by mTORC1 in Somatostatin Interneurons.
Artinian J, Jordan A, Khlaifia A, Honoré E, La Fontaine A, Racine AS, Laplante I, Lacaille JC. Artinian J, et al. Among authors: khlaifia a. J Neurosci. 2019 Oct 23;39(43):8439-8456. doi: 10.1523/JNEUROSCI.0728-19.2019. Epub 2019 Sep 13. J Neurosci. 2019. PMID: 31519824 Free PMC article.
13 results