Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
1956 2
1957 1
1959 1
1961 1
1962 1
1964 1
1966 1
1967 1
1968 3
1969 2
1970 1
1971 1
1973 2
1974 2
1977 2
1979 5
1980 3
1981 5
1982 2
1983 2
1985 2
1987 1
1988 2
1990 3
1991 1
1992 4
1993 4
1994 3
1995 1
1996 1
1997 3
1998 1
1999 4
2000 5
2001 3
2002 4
2004 1
2005 4
2006 7
2007 3
2008 1
2009 6
2010 1
2011 5
2012 1
2014 1
2015 3
2016 1
2017 2
2018 4
2019 5
2020 4
2021 9
2022 3
2023 1
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

135 results

Results by year

Filters applied: . Clear all
Page 1
Senolytics improve physical function and increase lifespan in old age.
Xu M, Pirtskhalava T, Farr JN, Weigand BM, Palmer AK, Weivoda MM, Inman CL, Ogrodnik MB, Hachfeld CM, Fraser DG, Onken JL, Johnson KO, Verzosa GC, Langhi LGP, Weigl M, Giorgadze N, LeBrasseur NK, Miller JD, Jurk D, Singh RJ, Allison DB, Ejima K, Hubbard GB, Ikeno Y, Cubro H, Garovic VD, Hou X, Weroha SJ, Robbins PD, Niedernhofer LJ, Khosla S, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: johnson ko. Nat Med. 2018 Aug;24(8):1246-1256. doi: 10.1038/s41591-018-0092-9. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988130 Free PMC article.
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.
Ogrodnik M, Zhu Y, Langhi LGP, Tchkonia T, Krüger P, Fielder E, Victorelli S, Ruswhandi RA, Giorgadze N, Pirtskhalava T, Podgorni O, Enikolopov G, Johnson KO, Xu M, Inman C, Palmer AK, Schafer M, Weigl M, Ikeno Y, Burns TC, Passos JF, von Zglinicki T, Kirkland JL, Jurk D. Ogrodnik M, et al. Among authors: johnson ko. Cell Metab. 2019 May 7;29(5):1061-1077.e8. doi: 10.1016/j.cmet.2018.12.008. Epub 2019 Jan 3. Cell Metab. 2019. PMID: 30612898 Free PMC article.
Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Among authors: johnson ko. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
Targeting senescent cells alleviates obesity-induced metabolic dysfunction.
Palmer AK, Xu M, Zhu Y, Pirtskhalava T, Weivoda MM, Hachfeld CM, Prata LG, van Dijk TH, Verkade E, Casaclang-Verzosa G, Johnson KO, Cubro H, Doornebal EJ, Ogrodnik M, Jurk D, Jensen MD, Chini EN, Miller JD, Matveyenko A, Stout MB, Schafer MJ, White TA, Hickson LJ, Demaria M, Garovic V, Grande J, Arriaga EA, Kuipers F, von Zglinicki T, LeBrasseur NK, Campisi J, Tchkonia T, Kirkland JL. Palmer AK, et al. Among authors: johnson ko. Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111/acel.12950. Epub 2019 Mar 25. Aging Cell. 2019. PMID: 30907060 Free PMC article.
Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice.
Ogrodnik M, Evans SA, Fielder E, Victorelli S, Kruger P, Salmonowicz H, Weigand BM, Patel AD, Pirtskhalava T, Inman CL, Johnson KO, Dickinson SL, Rocha A, Schafer MJ, Zhu Y, Allison DB, von Zglinicki T, LeBrasseur NK, Tchkonia T, Neretti N, Passos JF, Kirkland JL, Jurk D. Ogrodnik M, et al. Among authors: johnson ko. Aging Cell. 2021 Feb;20(2):e13296. doi: 10.1111/acel.13296. Epub 2021 Jan 20. Aging Cell. 2021. PMID: 33470505 Free PMC article.
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, Palmer AK, Chen T, Schaefer K, Justice JN, Nambiar AM, Musi N, Kritchevsky SB, Chen J, Khosla S, Jurk D, Schafer MJ, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: johnson ko. EBioMedicine. 2022 Mar;77:103912. doi: 10.1016/j.ebiom.2022.103912. Epub 2022 Mar 13. EBioMedicine. 2022. PMID: 35292270 Free PMC article.
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
Xu M, Tchkonia T, Ding H, Ogrodnik M, Lubbers ER, Pirtskhalava T, White TA, Johnson KO, Stout MB, Mezera V, Giorgadze N, Jensen MD, LeBrasseur NK, Kirkland JL. Xu M, et al. Among authors: johnson ko. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6301-10. doi: 10.1073/pnas.1515386112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578790 Free PMC article.
Neural coding.
Johnson KO. Johnson KO. Neuron. 2000 Jun;26(3):563-6. doi: 10.1016/s0896-6273(00)81193-9. Neuron. 2000. PMID: 10896153 Free article. Review. No abstract available.
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance.
Zhang X, Pearsall VM, Carver CM, Atkinson EJ, Clarkson BDS, Grund EM, Baez-Faria M, Pavelko KD, Kachergus JM, White TA, Johnson RK, Malo CS, Gonzalez-Suarez AM, Ayasoufi K, Johnson KO, Tritz ZP, Fain CE, Khadka RH, Ogrodnik M, Jurk D, Zhu Y, Tchkonia T, Revzin A, Kirkland JL, Johnson AJ, Howe CL, Thompson EA, LeBrasseur NK, Schafer MJ. Zhang X, et al. Among authors: johnson ko. Nat Commun. 2022 Sep 27;13(1):5671. doi: 10.1038/s41467-022-33226-8. Nat Commun. 2022. PMID: 36167854 Free PMC article.
135 results