Abstract
Disruption of function of left, but not right, lateral prefrontal cortex (LPFC) with low-frequency repetitive transcranial magnetic stimulation (rTMS) increased choices of immediate rewards over larger delayed rewards. rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Analysis of Variance
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Brain Mapping*
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Choice Behavior / physiology*
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Electric Stimulation / methods
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Electroencephalography / methods
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Female
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Functional Laterality / physiology*
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Humans
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Image Processing, Computer-Assisted / methods
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Judgment / physiology
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Magnetic Resonance Imaging / methods
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Male
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Models, Neurological
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Neuropsychological Tests
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Oxygen / blood
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Photic Stimulation
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Prefrontal Cortex / blood supply
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Prefrontal Cortex / physiology*
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Reaction Time / physiology
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Reward
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Self Concept*
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Transcranial Magnetic Stimulation / methods
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Young Adult