CellProfiler Analyst: data exploration and analysis software for complex image-based screens

BMC Bioinformatics. 2008 Nov 15:9:482. doi: 10.1186/1471-2105-9-482.

Abstract

Background: Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment.

Results: Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and analysis of multidimensional data, particularly data from high-throughput, image-based experiments.

Conclusion: The system enables interactive data exploration for image-based screens and automated scoring of complex phenotypes that require combinations of multiple measured features per cell.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Artificial Intelligence
  • Cells / ultrastructure*
  • Computational Biology / methods*
  • Image Processing, Computer-Assisted / methods*
  • Phenotype*
  • Software*