Spatiotemporal structure in large neuronal networks detected from cross-correlation

Neural Comput. 2006 Oct;18(10):2387-413. doi: 10.1162/neco.2006.18.10.2387.

Abstract

The analysis of neuronal information involves the detection of spatiotemporal relations between neuronal discharges. We propose a method that is based on the positions (phase offsets) of the central peaks obtained from pairwise cross-correlation histograms. Data complexity is reduced to a one-dimensional representation by using redundancies in the measured phase offsets such that each unit is assigned a "preferred firing time" relative to the other units in the group. We propose two procedures to examine the applicability of this method to experimental data sets. In addition, we propose methods that help the investigation of dynamical changes in the preferred firing times of the units. All methods are applied to a sample data set obtained from cat visual cortex.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology
  • Animals
  • Cats
  • Models, Neurological*
  • Nerve Net / physiology*
  • Neurons / physiology*
  • Nonlinear Dynamics
  • Photic Stimulation / methods
  • Statistics as Topic*
  • Stochastic Processes
  • Time Factors
  • Visual Cortex / cytology
  • Visual Cortex / physiology