Abstract
Research findings related to the functional significance of the gustatory neocortical system of the rat are reviewed and interpreted. Studies of gustatory neocortex (GN) involvement in taste-related cognitive processes are emphasized after briefly reviewing GN anatomy and physiology. Evidence is presented supporting the conclusion that the GN contributes relatively little to fundamental taste reactivity, but is deeply involved in cognitive (learning and memorial) taste processes; that is, “reactive salience” to taste stimuli is preserved following GN ablation, while “associative salience” is markedly degraded. Apparent functional similarities between GN and other sensory neocortical areas are emphasized throughout the paper, and a hierarchical view of gustatory system functioning is addressed.
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Reference Notes
Lasiter, P. S., & Glanzman, D. L. Thalamic and cortical projections of the pontine taste area: A retrograde fluorescent dual-labeling study. Manuscript in preparation, 1982.
Kiefer, S. W., Leach, L. R., & Braun, J. J. Taste agnosiafollowing gustatory neocortex ablation: Dissociation from odor and generality across taste species. Manuscript submitted for publication, 1981.
Ouellet, J. V., Kower, H. S., & Braun, J. J. Failure to retain a learned taste aversion after lesions of the gustatory neocortex. Paper presented at the meeting of the Western Psychological Association, Sacramento, April, 1975
References
Ables, M. F., & Benjamin, R. M. Thalamic relay for taste in the albino rat. Journal of Neurophysiology, 1960, 23, 376–382.
Adrian, E. D. Olfactory reactions in the brain of the hedgehog. Journal of Physiology (London), 1942, 100, 459–473.
Aggleton, J. P., Petrides, M., & Iversen, S. D. Differential effects of amygdaloid lesions on conditioned taste aversion learning by rats. Physiology & Behavior, 1981, 27, 397–400.
Allen, W. F. Origin and distribution of the tractus solitarius in the guinea pig. Journal of Comparative Neurology, 1923, 35, 171–204.
Altman, J. Effects of lesions in central nervous visual structures on light aversion of rats. American Journal of Physiology, 192, 202, 1208-1210.
ÅstrÖm, K. E. On the central course of afferent fibers in the trigeminal, facial, glosopharyngeal, and vagal nerves and their nuclei in the mouse. Acta Physiologica Scandinavica (Suppl. 106), 1953, 29, 209–320.
Bagshaw, M. H., & Pribram, K. H. Cortical organization in gustation (Macaca mulatto). Journal of Neurophysiology, 1953, 16, 499–508.
Barker, L. M., Best, M. R., & Domjan, M. (Eds.). Learning mechanisms in food selection. Waco, Tex: Baylor University Press, 1977.
Barnett, S. A. Experiments on “neophobia” in wild and laboratory rats. British Journal of Psychology, 1958, 49, 195–201.
Bartoshuk, L. M. Water taste in man. Perception & Psychophysics, 1968, 3, 69–72.
Bartoshuk, L. The chemical senses. I. Taste. In J. W. Kling & L. A. Riggs (Eds.), “Woodworth and Schlosberg”s experimental psychology (3rd ed. ). New York: Holt, Rinehart & Winston, 1971.
Beidler, L. M. Properties of chemoreceptors of tongue of rat. Journal of Neurophysiology, 1953, 16, 595–607.
Beidler, L. M. A theory of taste stimulation. Journal of General Physiology, 1954, 38, 133–139.
Beidler, L. M. Taste receptor stimulation. In J. A. V. Butler, H. E. Huxley, & R. E. Zirkle (Eds.), Progress in biophysics and biophysical chemistry (Vol. 12). New York: Pergamon Press, 1961.
Benjamin, R. M. Cortical taste mechanisms studied by two different test procedures. Journal of Comparative and Physiological Psychology, 1955, 48, 119–122. (a)
Benjamin, R. M. The effect of fluid deprivation on taste deficits following cortical lesions. Journal of Comparative and Physiological Psychology, 1955, 48, 502–505. (b)
Benjamin, R. M. The absence of deficits in taste discrimination following cortical lesions as a function of the amount of preoperative practice. Journal of Comparative and Physiological Psychology, 1959, 52, 255–258.
Benjamin, R. M. Effect of removal of olfactory bulbs on taste discrimination in normal and brain operated rats. The Physiologist, 1960, 3, 19. (Abstract)
Benjamin, R. M., & Akert, K. Cortical and thalamic areas involved in taste discrimination in the albino rat. Journal of Comparative Neurology, 1959, 111, 231–259.
Benjamin, R. M., & Pfaffmann, C. Cortical localization of taste in the albino rat. Journal of Neurophysiology, 1955, 18, 56–64.
Berger, B. D., Wise, C. D., & Stein, L. Area postrema damage and bait shyness. Journal of Comparative and Physiological Psychology, 1973, 82, 475–479.
Best, P. J., & Zuckerman, K. Subcortical mediation of learned taste aversion. Physiology & Behavior, 1971, 7, 317–320.
Blomquist, A. J., Benjamin, R. M., & Emmers, R. Thalamic localization of afferents from the tongue in squirrel monkeys (Saimiri sciureus). Journal of Comparative Neurology, 1962, 118, 77–87.
Blum, M., Ruch, T. C., & Walker, A. E. Localization of taste in the thalamus of Macaca mulatto. Yale Journal of Biology and Medicine, 1943, 12, 719–736.
BÖrnstein, W. S. The cortical taste area in monkeys and a semiquantitative method of testing taste in monkeys. American Journal of Physiology, 1940, 129, 314. (a)
BÖrnstein, W. S. Cortical representation of taste in man and monkey. I: Functional and anatomical relations of taste, olfaction, and somatic sensibility. Yale Journal of Biology and Medicine, 1940, 12, 719–736. (b)
BÖrnstein, W. S. Cortical representation of taste in man and monkey. II: The localization of the cortical taste area in man and a method of measuring impairment of taste in man. Yale Journal of Biology and Medicine, 1940, 13, 133–156. (c)
Braun, J. J. The neocortex and visual placing in rats. Brain Research, 1966, 1, 381–394.
Braun, J. J. Neocortex and feeding behavior in the rat. Journal of Comparative and Physiological Psychology, 1975, 89, 507–522.
Braun, J. J. Time and recovery from brain damage. In S. Finger (Ed.), Recovery from brain damage. New York: Plenum Press, 1978.
Braun, J. J., & Kiefer, S. Preference-aversion functions for the basic taste stimuli in rats lacking gustatory neocortex. Bulletin of the Psychonomic Society, 1975, 6, 438–439. (Abstract)
Braun, J. J., Kiefer, S. W., & Ouellet, J. V. Psychic ageusia in rats lacking gustatory neocortex. Experimental Neurology, 1981, 72, 711–716.
Braun, J. J., Leach, L, R., & Kiefer, S. W. Psychic ageusia in rats lacking gustatory neocortex. Bulletin of the Psychonomic Society, 1978, 12, 267. (Abstract)
Braun, J. J., Lundey, E., & McCarthy, F. Depth discrimination in rats following removal of visual neocortex. Brain Research, 1970, 20, 283–291.
Braun, J. J., & Rosenthal, B. Relative salience of saccharin and quinine in long-delay taste aversion learning. Behavioral Biology, 1976, 16, 341–352.
Braun, J. J., & Ryugo, R. A. Taste facilitation of a learned odor aversion. Bulletin of the Psychonomic Society, 1974, 4, 253. (Abstract)
Braun, J. J., Slick, T. B., & Lorden, J. F. Involvement of gustatory neocortex in the learning of taste aversions. Physiology & Behavior, 1972, 9, 637–641.
Burešova, O., & Bures, J. Cortical and subcortical components of conditioned saccharin aversion in rats. Acta Neurologia Experimentons, 1973, 33, 689–698.
Burton, H., & Benjamin, R. M. Central projections of the gustatory system. In L. M. Beidler (Ed.), Handbook of sensory physiology (Vol. 4): Chemical senses, 2. New York: Springer-Verlag, 1971.
Cooper, R. M., Freeman, I., & Pinel, J. P. Absolute threshold of vision in the rat after removal of striate cortex. Journal of Comparative and Physiological Psychology, 1967, 64, 36–39.
Corey, D. T. The determinants of exploration and neophobia. Neuroscience and Biobehavioral Reviews, 1978, 2, 235–253.
Crosby, E. C., Humphrey, T., & Lauer, E. W. Correlative anatomy of the nervous system. New York: Macmillan, 1962.
Divac, I., Gade, A., & Wikmark, R. E. G. Taste aversion in rats with lesions in the frontal lobes: No evidence for interoceptive agnosia. Physiological Psychology, 1975, 3, 43–46.
Doetsch, G. S., & Erickson, R. P. Synaptic processing of tastequality information in the nucleus tractus solitarius of the rat. Journal of Neurophysiology, 1970, 33, 490–507.
Domjan, M. Ingestional aversion learning: Unique and general processes. In J. Rosenblatt, R. Hinde, C. Beer, & M. Busnel (Eds.), Advances in the study of behavior (Vol. 11). New York: Academic Press, 1980.
Eichenbaum, H., Shedlack, K. J., & Eckmann, K. W. Thalamocortical mechanisms in odor-guided behavior. I. Effects of lesions of the mediodorsal thalamic nucleus and frontal cortex on olfactory discrimination in the rat. Brain, Behavior, and Evolution, 1980, 17, 255–275.
Emmers, R. Separate cortical receiving areas for gustatory and tongue tactile afferents in the rat. Anatomical Record, 1966, 154, 460.
Emmers, R. Tonic control of water intake via the thalamic taste nucleus. Annals of the New York Academy of Sciences, 1977, 290, 124–138.
Emmers, R., Benjamin, R. N., & Blomquist, A. J. Thalamic localization from the tongue in albino rats. Journal of Comparative Neurology, 1962, 118, 43–48.
Erickson, R. P. Sensory neural patterns and gustation. In Y. Zotterman (Ed.), Olfaction and taste (Vol. 1). Oxford: Pergamon Press, 1963.
Ferrier, D. The functions of the brain. London: Smith, Elder, 1886.
Finger, S., Marshak, R. A., Cohen, M., Scheff, S., Trace, R., & Neimand, D. Effects of successive and simultaneous lesions of somatosensory cortex on tactile discrimination in the rat. Journal of Comparative and Physiological Psychology, 1971, 77, 221–227.
Fink, R. P., & Heimer, L. Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system. Brain Research, 1967, 4, 369–374.
Fregly, M. J. Specificity of the sodium chloride appetite of adrenalectomized rats: Substitution of lithium chloride for sodium chloride. American Journal of Physiology, 1958, 195, 645–653.
French, R. L. The function of the cerebral cortex of the rat in the discrimination of simple auditory rhythms. Journal of Comparative Psychology, 1942, 33, 1–32.
Frommer, G. P. Gustatory afferent responses in the thalamus. In M. R. Kare & B. Halpern (Eds.), The physiological and behavioral aspects of taste. Chicago: University of Chicago Press, 1961.
Ganchrow, J. R., & Erickson, R. P. Neural correlates of gustatory intensity and quality. Journal of Neurophysiology, 1970, 33, 768–783.
Ganchrow, D., & Erickson, R. P. Thalamocortical relations in gustation. Brain Research, 1972, 36, 289–305.
Garcia, J., & Ervin, F. R. Gustatory-visceral and telereceptor-cutaneous conditioning: Adaptation in internal and external milieus. Communications in Behavioral Biology, 1968, 1, 389–415.
Garcia, J., Ervin, F. R., Yorke, C. H., & Koelling, R. A. Conditioning with delayed vitamin injections. Science, 1967, 155, 716–717.
Garcia, J., Kimeldorf, D. J., & Koelling, R. A. Conditioned aversion to saccharin resulting from exposure to gamma radiation. Science, 1955, 122, 157–158.
Garcia, J., & Rusiniak, K. W. What the nose learns from the mouth. In D. Muller-Schwarze & R. N. Silverstein (Eds.), Chemical signals. New York: Plenum Press, 1980.
Giachetti, I., & MacLeod, P. Olfactory input to the thalamus: Evidence for a ventroposteromedial projection. Brain Research, 1977, 125, 166–169.
Gold, R. M., & Proulx, D. M. Bait-shyness acquisition is impaired by VMH lesions that produce obesity. Journal of Comparative and Physiological Psychology, 1972, 79, 201–209.
Goldberger, M. E. Recovery of movement after CNS lesions in monkeys. In D. G. Stein, J. J. Rosen, & N. Butters (Eds.), Plasticity and recovery of function in the central nervous system. New York: Academic Press, 1974.
Grill, H. J. Sucrose as an aversive stimulus. Neuroscience Ab stracts, 1975, 1, 525.
Grill, H. J., & Norgren, R. The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Research, 1978, 143, 263–279. (a)
Grill, H. J., & Norgren, R. The taste reactivity test. II. Mimetic responses to gustatory stimuli in chronic thalamic and chronic decerebrate rats. Brain Research, 1978, 143, 281–297. (b)
Grill, H. J., & Norgren, R. Chronic decerebrate rats demonstrate satiation but not bait-shyness. Science, 1978, 201, 267–269. (c)
Hankins, W. G., Garcia, J., & Rusiniak, K. W. Cortical lesions: Flavor illness and noise-shock conditioning. Behavioral Biology, 1974, 10, 173–181.
Head, H., & Holmes, G. Sensory disturbance from cerebral lesions. Brain, 1911, 34, 102–225.
Horel, J. A., Bettinger, L. A., Royce, G. J., & Meyer, D. R. Role of neocortex in the learning and relearning of two visual habits by the rat. Journal of Comparative and Physiological Psychology, 1966, 61 66-78.
Hull, C. L. Stimulus intensity dynamism (V) and stimulus generalization. Psychological Review, 1949, 56, 67–76.
Jackson, J. H. Evolution and dissolution of the nervous system. In J. Taylor (Ed.), Selected writings of John Hughlings Jackson (Vol. 2). New York: Basic Books, 1958. (Originally published, 1884. )
Jacobs, H. L. The osmotic postingestion factor in the regulation of glucose appetite. In M. R. Kare & B. P. Halpern (Eds.), The physiological and behavioral aspects of taste. Chicago: University of Chicago Press, 1961.
Kalat, J. W. Taste salience depends on novelty, not concentration, in taste-aversion learning in the rat. Journal of Comparative and Physiological Psychology, 1974, 86, 47–50.
Kalat, J. W., & Rozin, P. “Salience”: A factor which can override temporal contiguity in taste-aversion learning. Journal of Comparative and Physiological Psychology, 1970, 71, 192–197.
Kalat, J. W., & Rozin, P. “Learned safety” as a mechanism in long-delay taste-aversion learning in rats. Journal of Comparative and Physiological Psychology, 1973, 83, 198–207.
Kawamura, U., Kasahara, Y., & Funakoshi, M. A possible brain mechanism for rejection behavior to strong salt solution. Physiology & Behavior, 1970, 5, 67–74.
Kiefer, S. W. Two-bottle discrimination of equimolar NaCl and LiCl solutions by rats. Physiological Psychology, 1978, 6, 191–198.
Kiefer, S. W., & Braun, J. J. Absence of differential associative responses to novel and familiar taste stimuli in rats lacking gustatory neocortex. Journal of Comparative and Physiological Psychology, 1977, 91, 498–507.
Kiefer, S. W., & Braun, J. J. Acquisition of taste avoidance habits in rats lacking gustatory neocortex. Physiological Psychology, 1979, 7, 245–250.
Kiefer, S. W., Rusiniak, K. W., & Garcia, J. Flavor-illness aversions: Potentiation of odor by taste in rats with gustatory neocortex ablations. Journal of Comparative and Physiological Psychology, in press.
Kolb, B., & Nonneman, A. Prefrontal cortex and the regulation of food intake in the rat. Journal of Comparative and Physiological Psychology, 1975, 88, 806–815.
Kral, P. A. Interpolation of electroconvulsive shock during CS-US interval as an impediment to the conditioning of taste aversion. Psychonomic Science, 1970, 19, 36–37.
Kratz, C. M., & Levitsky, D. A. Post-ingestive effects of quinine on intake of nutritive and non-nutritive substances. Physiology & Behavior, 1978, 21, 851–854.
Krettek, J. E., & Price, J. L. A direct input from the amygdala to the thalamus and the cerebral cortex. Brain Research, 1974, 67, 169–174.
Krettek, J. E., & Price, J. L. The cortical projection of the medio-dorsal nucleus and adjacent thalamic nuclei in the rat. Journal of Comparative Neurology, 1977, 171, 157–192. (a)
Krettek, J. E., & Price, J. L. Projections from the amygdaloid complex to the cerebral cortex and thalamus in the rat and cat. Journal of Comparative Neurology, 1977, 172, 687–722. (b)
Krettek, J. E., & Price, J. L. Projections from the amygdaloid complex and adjacent olfactory structures to the entorhinal cortex and to the subiculum in the rat and cat. Journal of Comparative Neurology, 1977, 172, 723–752. (c)
Krettek, J. E., & Price, J. L. Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat. Journal of Comparative Neurology, 1978, 178, 225–254.
Krieckhaus, E. E. “Innate recognition” aids rats in sodium regulation. Journal of Comparative and Physiological Psychology, 1970, 73, 117–122.
Ladd, G. T. Elements of physiological psychology. New York: Scribner’s, 1887.
Lashley, K. S. Studies of cerebral function in learning. II. The effects of long continued practice upon cerebral localization. Journal of Comparative Psychology, 1921, 1 453-468.
Lashley, K. S. The mechanism of vision: II. The influence of cerebral lesions upon the threshold of discrimination for brightness in the rat. Journal of Genetic Psychology, 1930, 37, 461–480.
Lashley, K. S. The mechanism of vision: XII. Nervous structures concerned in habits based on reactions to light. Comparative Psychology Monograph, 1935, 11, 43–79.
Lashley, K. S. The mechanism of vision: XVII. Autonomy of the visual cortex. Journal of Genetic Psychology, 1942, 60, 197–221.
Lashley, K. S. In search of the engram. Symposium of the Society of Experimental Biology, 1950, 4, 454–482.
Lashley, K. S. Studies of cerebral functions in learning. XI. The behavior of the rat in the latch box situations. In F. A. Beach, D. O. Hebb, C. T. Morgan, & H. W. Nissen (Eds.), The neuropsychology of Lashley. New York: McGraw-Hill, 1960. (Originally published, 1935. )
Lasiter, P. S., & Glanzman, D. L. Cortical substrates of taste aversion learning: Dorsal prepiriform (insular) lesions disrupt taste aversion learning. Journal of Comparative and Physiological Psychology, 1982, 96, 376–392.
Lasiter, P. S., Glanzman, D. L., & Mensah, P. A. Direct connectivity between pontine taste areas and gustatory neocortex in rat. Brain Research, 1982, 234, 111–121.
Lehr, P. P., & Nachman, M. Lateralization of learned taste aversion by cortical spreading depression. Physiology & Behavior, 1973, 10, 79–83.
Leonard, C. M. The prefrontal cortex of the rat. I. Cortical projection of the mediodorsal nucleus. II. Efferent connections. Brain Research, 1969, 12, 321–343.
Leonard, C. M. The connections of the dorsomedial nuclei. Brain, Behavior and Evolution, 1972, 6, 524–541.
LeVere, T. E. Recovery of function after brain damage: A theory of the behavioral deficit. Physiological Psychology, 1980, 8, 297–308.
LeVere, T. E., & Mills, J. Residual differential brightness thresholds following removal of visual neocortex in rats. Physiological Psychology, 1977, 5, 490–496.
Lorden, J. F. Effects of lesions of the gustatory neocortex on taste aversion learning. Journal of Comparative and Physiological Psychology, 1976, 90, 665–679.
Loullis, C. C., Wayner, M. J., & Jolicoeur, F. B. Thalamic taste nuclei lesions and taste aversion learning. Physiology & Behavior, 1978, 20, 653–655.
Luria, A. R. Higher cortical functions in man. New York: Basic Books, 1966.
Macht, M. B. Subcortical localization of certain “taste” responses in the cat. Federation Proceedings, 1951, 10, 88. (Abstract)
Maclean, P. D. Cerebral evolution and emotional processes. Annals of the New York Academy of Sciences, 1972, 193, 137–149.
McBurney, D. H. Are there primary tastes for man? In Chemical senses and flavor (Vol. 1). Dordrecht: Reidel, 1974.
McCleary, R. A. Taste and postingestion factors in specific hunger behavior. Journal of Comparative and Physiological Psychology, 1953, 46, 411–421.
McCleary, R. A. Response-modulating functions of the limbic system: Initiation and suppression. In E. Stellar & J. Sprague (Eds.), Progress in physiological psychology (Vol. 1). New York: Academic Press, 1966.
McGowan, B. K., Garcia, J., Ervin, F. R., & Schwartz, J. Effects of septal lesions on bait-shyness in the rat. Physiology & Behavior, 1969, 4, 907–909.
McGowan, B. K., Hankins, W. G., & Garcia, J. Limbic lesions and control of the internal and external environment. Behavioral Biology, 1972, 7, 841–852.
Meyer, D. R. Access to engrams. American Psychologist, 1972, 27, 124–133.
Meyer, D. R., & Beattie, M. S. Some properties of substrates of memory. In L. H. Miller, C. A. Sandman, & A. J. Kastin (Eds.), Neuropeptide influences of the brain and behavior. New York: Raven Press, 1977.
Meyer, D. R., & Meyer, P. M. Dynamics and bases of recoveries of functions after injuries to the cerebral cortex. Physiological Psychology, 1977, 5, 133–165.
Miller, C. R., Elkins, R. L., & Peacock, L. J. Disruption of a radiation-induced preference shift by hippocampal lesions. Physiology & Behavior, 1971, 6, 283–285.
Miller, S. D., & Erickson, R. P. The odor of taste solutions. Physiology & Behavior, 1966, 1, 145–146.
Mook, D. G. Oral and postingestion factors in specific hunger behavior. Journal of Comparative and Physiological Psychology, 1963, 56, 654–659.
Morest, D. K. Experimental study of the projections of the nucleus of the tractus solitarius and the area postrema in the cat. Journal of Comparative Neurology, 1967, 130, 277–300.
Munk, H. Uber die Functionen der Grosshirnrinde. Berlin: Hirschwald, 1890.
Nachman, M. Learned aversion to the taste of lithium chloride and generalization to other salts. Journal of Comparative and Physiological Psychology, 1963, 56, 343–349.
Nachman, M. Limited effects of electroconvulsive shock on memory of taste stimulation. Journal of Comparative and Physiological Psychology, 1970, 73, 31–37.
Nachman, M., & Ashe, J. H. Effects of basolateral amygdala lesions on neophobia, learned taste aversions, and sodium ap-petite in rats. Journal of Comparative and Physiological Psychology, 1974, 87, 622–643.
Nadal, L. Interhemispheric transfer: Monocular input and varied sensory conditions. Physiology & Behavior, 1971, 6, 655–661.
Nauta, W. J. H. Silver impregnation of degenerating axons. In W. F. Windle (Ed.), New research techniques of neuroanatomy. Springfield, Ill: Thomas, 1957.
Norgren, R. Gustatory responses in the hypothalamus. Brain Research, 1970, 21, 63–77. (a)
Norgren, R. Behavioral correlates of the thalamic gustatory area. Brain Research, 1970, 22, 221–230. (b)
Norgren, R. Gustatory afferents to ventral forebrain. Brain Research, 1974, 81, 285–295.
Norgren, R. Taste pathways to hypothalamus and amygdala. Journal of Comparative Neurology, 1976, 166, 17–30.
Norgren, R. A synopsis of gustatory neuroanatomy. In J. LeMagnen & P. Macleod (Eds.), Olfaction and taste VI. London: Information Retrieval, 1977.
Norgren, R. Projections from the nucleus of the solitary tract in rat. Neuroscience, 1978, 3, 207–218.
Norgren, R., & Leonard, C. M. Taste pathways in rat brainstem. Science, 1971, 173, 1136–1139.
Norgren, R., & Leonard, C. M. Ascending central gustatory connections. Journal of Comparative Neurology, 1973, 150, 217–238.
Norgren, R., & Pfaffmann, C. The pontine taste area in the rat. Brain Research, 1975, 91, 99–117.
Norgren, R., & Wolf, G. Projections of thalamic gustatory and lingual areas in the rat. Brain Research, 1975, 92, 123–129.
Nowlis, G. H. Taste elicited tongue movements in human newborn infants: An approach to palatability. In J. F. Bosma (Ed.), Fourth Symposium on Oral Sensation and Perception: Development in the fetus and infant (Department of Health, Education, and Welfare Publication No. NIH 73-546). Washington, D. C: U. S. Government Printing Office, 1973.
Nowlis, G. H. Conditioned stimulus intensity and acquired alimentary aversions in the rat. Journal of Comparative and Physiological Psychology, 1974, 86, 1173–1184.
Nowlis, G. H. From reflex to representation: Taste-elicited tongue movements in the human newborn. In J. M. Weiffenbach (Ed.), Taste and development: The genesis of sweet preference (Department of Health, Education, and Welfare Publication No. NIH 77-1068). Washington, D. C: U. S. Government Printing Office, 1977.
Nowlis, G. H., & Kessen, W. Human newborns differentiate differing concentrations of sucrose and glucose. Science, 1976, 191, 865–866.
Oakley, B. Impaired operant behavior following lesions of the thalamic taste nucleus. Journal of Comparative and Physiological Psychology, 1965, 59, 202–210.
Oakley, B., & Pfaffmann, C. Electrophysiologically monitored lesions in the gustatory thalamic relay of the albino rat. Journal of Comparative and Physiological Psychology, 1962, 55, 155–160.
Papez, J. W. A proposed mechanism of emotion. American Medical Association Archives of Neurology and Psychiatry, 1937, 38, 725–743.
Patton, H. D. Physiology of smell and taste. Annual Review of Physiology, 1950, 12, 469–484.
Patton, H. D. Taste, olfaction and visceral sensation. In J. F. Fulton (Ed.), A textbook of physiology (17th ed. ). Philadelphia: Saunders, 1955.
Patton, H. D., & Amassian, V. E. Cortical projection zone of chorda typani nerve in cat. Journal of Neurophysiology, 1952, 15, 245–250.
Patton, H. D., & Ruch, T. C. “Howell”s textbook of physiology (15th ed. ). Philadelphia: Saunders, 1946.
Patton, H. D., Ruch, T. C., & Fulton, J. F. The relation of the foot of the pre- and postcentral gyrus to taste in the monkey and chimpanzee. Federation Proceedings, 1946, 5, 79.
Patton, H. D., Ruch, T. C., & Walker, A. E. Experimental hypogeusia from Horsley-Clarke lesions of the thalamus in Macaca mulatto. Journal of Neurophysiology, 1944, 7, 171–184.
Pavlov, I. P. Conditioned reflexes. New York: Dover, 1960. (Originally published, 1927. )
Pellegrino, L. Amygdaloid lesions and behavioral inhibition in the rat. Journal of Comparative and Physiological Psychology, 1968, 65, 483–491.
Perrotto, R. S., & Scott, T. R. Gustatory neural coding in the pons. Brain Research, 1976, 110, 283–300.
Petrinovich, L. Cortical spreading depression and memory transfer: A methodological critique. Behavioral Biology, 1976, 16, 79–84.
Pfaffmann, C. Gustatory afferent impulses. Journal of Cellular and Comparative Physiology, 1941, 17, 243–258.
Pfaffmann, C. The sense of taste. In J. Field, H. W. Magoun, & V. E. Hall (Eds.), Handbook of physiology (Vol. 1). Washington, D. C: American Physiological Society, 1959.
Pfaffmann, C. The pleasures of sensation. Psychological Review, 1960, 67, 253–268.
Pfaffmann, C. De Gustibus. American Psychologist, 1965, 20, 21–33.
Pfaffmann, C. Taste preference and reinforcement. In J. Tapp (Ed.), Reinforcement and behavior. New York: Academic Press, 1969.
Pfaffmann, C. Physiological and behavioral processes of the sense of taste. In G. Wolstenholme & J. Knight (Eds.), Ciba Foundation Symposium on Taste and Smell in Vertebrates. London: Churchill, 1970.
Pfaffmann, C., Frank, M., & Norgren, R. Neural mechanisms and behavioral aspects of taste. Annual Review of Psychology, 1979, 30, 283–325.
Pfaffmann, C., Norgren, R., & Grill, H. J. Sensory affect and motivation. Annals of the New York Academy of Science, 1977, 290, 18–34.
Phillips, J. Taste discrimination, generalization, and the gustatory neocortex. Unpublished master”s thesis, Arizona State University, 1977.
Powell, T. P. S., Cowan, W. M., & Raisman, G. The central olfactory connexions. Journal of Anatomy, 1965, 99, 791–813.
Rescorla, R. A., & Wagner, A. R. A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement. In A. H. Black & W. F. Prokasy (Eds.), Classical conditioning0 (Vol. 2): Current research and theory. New York: Appleton-Century-Crofts, 1972.
Revusky, S. H., & Bedarf, E. W. Association of illness with ingestion of novel foods. Science, 1967, 155, 219–220.
Revusky, S., & Garcia, J. Learned associations over long delays. In G. H. Bower & J. T. Spence (Eds.), Psychology of learning and motivation: Advances in research and theory (Vol. 4). New York: Academic Press, 1970.
Ricardo, J. A., & Koh, E. T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Research, 1978, 153, 1–26.
Richter, C. P. Salt taste thresholds of normal and adrenalectomized rats. Endocrinology, 1939, 24, 367–371.
Richter, C. P. Self-regulatory functions. Harvey Lectures, 1942, Series 38, 63-103.
Richter, C. P. Experimentally produced behavior reactions to food poisoning in wild and domesticated rats. Annals of the New York Academy of Sciences, 1953, 56, 225–239.
Roll, D. L., & Smith, J. C. Conditioned taste aversion in anesthetized rats. In M. E. P. Seligman & J. L. Hager (Eds.), Biological boundaries of learning. New York: Appleton-Century-Crofts, 1972.
Rolls, B. J., & Rolls, E. T. Effects of lesions in the baso-lateral amygdala on fluid intake in the rat. Journal of Comparative and Physiological Psychology, 1973, 83, 240–247.
Roth, S. R., Schwartz, M., & Teitelbaum, P. Failure of recovered lateral hypothalamic rats to learn specific food aversions. Journal of Comparative and Physiological Psychology, 1973, 83, 184–197.
Rozin, P., & Kalat, J. W. Specific hungers and poison avoidance as adaptive specializations of learning. Psychological Review, 1971, 78, 459–486.
Ruch, T. C, Patton, H. D., Woodbury, J. W., & Towe, A. L. Neurophysiology (6th ed. ). Philadelphia: Saunders, 1966.
Ruderman, M. I., Morrison, A. R., & Hand, P. J. A solution to the problem of cerebral cortical localization of taste in cat. Experimental Neurology, 1972, 37, 522–537.
Rzoska, J. Bait shyness, a study in rat behaviour. British Journal of Animal Behaviour, 1953, 1, 128–135.
Schwartz, J., & Teitelbaum, P. Dissociation between learning and remembering in rats with lesions in the lateral hypothalamus. Journal of Comparative and Physiological Psychology, 1974, 87, 384–398.
Scott, T. R. Behavioral support for a neural taste theory. Physiology & Behavior, 1974, 12, 413–417.
Scott, T. R., & Erickson, R. P. Synaptic processing of taste-quality information in the thalamus of the rat. Journal of Neurophysiology, 1971, 34, 668–684.
Scott, T. R., & Perrotto, R. S. Intensity coding in pontine taste area: Gustatory information is processed similarly through out rat’s brain stem. Journal of Neurophysiology, 1980, 44, 739–749.
Smith, D. F., & Balagura, S. Role of oropharyngeal factors in LiCl aversion. Journal of Comparative and Physiological Psychology, 1969, 69, 308–310.
Smith, J. C., & Roll, D. L. Trace conditioning with X-rays as an aversive stimulus. Psychonomic Science, 1967, 9, 11–12.
Smith, K. U. The postoperative effects of removal of the striate cortex upon certain unlearned visually controlled reactions in the cat. Journal of Genetic Psychology, 1937, 50, 137–156.
Smith, K. U. Visual discrimination in the cat: VI. The relation between pattern vision and visual acuity and the optic projection centers of nervous system. Journal of Genetic Psychology, 1938, 53, 251–272.
Spear, P. D. Behavioral and neurophysiological consequences of visual cortex damage: Mechanisms of recovery. In J. M. Sprague & A. N. Epstein (Eds.), Progress in psychobiology and physiological psychology (Vol. 8). New York: Academic Press, 1979.
Spear, P. D., & Braun, J. J. Nonequivalence of normal and posteriorly neodecorticated rats on two brightness discrimination problems. Journal of Comparative and Physiological Psychology, 1969, 67, 235–239.
Sperry, R. W. Effect of crossing nerves to antagonistic limb muscles in the monkey. Archives of Neurology and Psychiatry, 1947, 58, 452–473.
Steiner, J. E. The human gustofacial response. InJ. F. Bosma (Ed.), Fourth Symposium on Oral Sensation and Perception: Development in the fetus and infant (Department of Health, Education, and Welfare Publication No. NIH 73-546). Washington, D. C: U. S. Government Printing Office, 1973.
Stellar, E., & McCleary, R. A. Food preference as a function of the method of measurement. American Psychologist, 1952, 7, 256.
Tapper, D. N., & Halpern, B. P. Taste stimuli: A behavioral categorization. Science, 1968, 161, 708–710.
Torvik, A. Afferent connections to the sensory trigeminal nuclei, the nucleus of the solitary tract and adjacent structures. An experimental study in the rat. Journal of Comparative Neurology, 1956, 106, 51–141.
Voshart, K., & Van der Kooy, D. The organization of the efferent projections of the parabrachial nucleus to the forebrain in the rat: A retrograde fluorescent double-labeling study. Brain Research, 1981, 212, 271–286.
Walker, A. E. An experimental study of the thalamocortical projection of the macaque monkey. Journal of Comparative Neurology, 1934, 64, 1–39.
Walker, A. E. The primate thalamus. Chicago: University of Chicago Press, 1938.
Winn, R. F., Kent, M. A., & Libkuman, T. Learned taste aversion induced by cortical spreading depression. Physiology & Behavior, 1975, 15, 21–24.
Wirsig, C. R., & Grill, H. J. The contribution of the rat’s neocortex to ingestive control: I. Latent learning for the taste of sodium chloride. Journal of Comparative and Physiological Psychology, in press.
Wolf, G. Projections of thalamic and cortical gustatory areas in the rat. Journal of Comparative Neurology, 1968, 132, 519–530.
Wolf, G. Innate mechanisms for regulation of sodium intake. In C. Pfaffmann (Ed.), Olfaction and taste: Proceedings of the Third International Symposium. New York: Rockefeller University Press, 1969.
Wolf, G., DiCara, L., & Braun, J. Sodium appetite in rats after neocortical ablation. Physiology & Behavior, 1970, 5, 1265–1269.
Wood, C. C., Spear, P. D., & Braun, J. J. Direction-specific eficits in horizontal optokinetic nystagmus following removal of visual cortex in the cat. Brain Research, 1973, 60, 231–237.
Woolsey, C. N. Organization of somatic sensory and motor areas of the cerebral cortex. In H. F. Harlow & C. N. Woolsey (Eds.), Biological and biochemical bases of behavior. Madison: University of Wisconsin Press, 1958.
Woolsey, C. N., & Le Messurier, D. H. Pattern of cutaneous representation in the rat’s cerebral cortex. Federation Proceedings, 1948, 7, 137–138.
Yamamoto, T., & Kawamura, Y. Summated cerebral responses to taste stimuli in rat. Physiology & Behavior, 1972, 9, 789–793.
Yamamoto, T., & Kawamura, Y. Cortical responses to electrical and gustatory stimuli in the rabbit. Brain Research, 1975, 94, 447–463.
Yamamoto, T., Matsuo, R., & Kawamura, Y. Localization of cortical gustatory area in rats and its role in taste discrimination. Journal of Neurophysiology, 1980, 44, 440–454.
Yamamoto, T., Yuyama, N., & Kawamura, Y. Cortical neurons responding to tactile, thermal and taste stimulations of the rat’s tongue. Brain Research, 1981, 221, 202–206.
Young, P. T. Hedonic organization and regulation of behavior. Psychological Review, 1966, 73, 59–86.
Zotterman, Y. Species differences in the water taste. Acta Physiologica Scandinavica, 1956, 37, 60–70.
Zotterman, Y. Discussion of cortical gustatory projection area on p. 112. In G. E. W. Wolstenholme & J. Knight (Eds.), Taste and smell in vertebrates. London: Churchill, 1970.
Zubek, J. P. Studies in somesthesis. I. Role of the somesthetic cortex in roughness discrimination in the rat. Journal of Comparative and Physiological Psychology, 1951, 44, 339–353. (Manuscript received February 6, 1982; accepted for publication February 10, 1982.)
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Research support was provided by N.I.H. Grants NB06788, NS08658, NS11616, Nutrition Foundation Grant 440 (with W. Kessen and G. Nowlis), and, most recently, by a Dean”s Research Award to J.B. (summer 1980), Institutional Biomedical Research Support Grant 935191 to D. Glanzman, and by generous assistance from research funds provided by the Department of Psychology, for which we are most grateful. We deeply appreciate the thoughtful and detailed editorial comments and suggestions offered by Dennis Glanzman, and the patience, skill, and good cheer of Pat Query who typed the manuscript. I (J.B.) should like to express gratitude to my dear friend, Geoffrey Nowlis, whose original ideas contributed to the heuristic framework for much of the research summarized, and the thoughts expressed, in the present paper, and to George Wolf, who first called my attention to the gustatory neocortex of the rat.
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Braun, J.J., Lasiter, P.S. & Kiefer, S.W. The gustatory neocortex of the rat. Psychobiology 10, 13–45 (1982). https://doi.org/10.3758/BF03327004
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DOI: https://doi.org/10.3758/BF03327004