Glia make up most of the cells in the brain, yet until recently they were believed to have only a passive, supporting role. It is now becoming increasingly clear that these cells have other functions: they make crucial contributions to the formation, operation and adaptation of neural circuitry.
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Further reading
Allen, N. J. & Barres, B. A. Signaling between glia and neurons: focus on synaptic plasticity. Curr. Opin. Neurobiol. 15, 542–548 (2005).
Barres, B. A. The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 60, 430–440 (2008).
Freeman, M. R. & Doherty, J. Glial cell biology in Drosophila and vertebrates. Trends Neurosci. 29, 82–90 (2006).
Haydon, P. G. & Carmignoto, G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol. Rev. 86, 1009–1031 (2006).
Kettenmann, H. & Ransom, B. R. (eds) Neuroglia 2nd edn (Oxford Univ. Press, 2005).
Nave, K.-A. & Trapp, B. D. Axon–glial signaling and the glial support of axon function. Annu. Rev. Neurosci. 31, 535–561 (2008).
Wang, D. D. & Bordey, A. The astrocyte odyssey. Prog. Neurobiol. 86, 342–367 (2008).
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Allen, N., Barres, B. Glia — more than just brain glue. Nature 457, 675–677 (2009). https://doi.org/10.1038/457675a
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DOI: https://doi.org/10.1038/457675a
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