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Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes

Nature volume 331, pages 143–145 (1988)Cite this article

Abstract

The Shaker gene of Drosophila melanogaster encodes a potassium-selective ion channel, the 'A' channel, or one of its subunits. A single Shaker messenger RNA species suffices to direct the synthesis of functional A channels in Xenopus oocytes. Physiological characteristics of the A currents induced by two different mRNA species are compared.

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Authors and Affiliations

  1. Howard Hughes Medical Institute and Departments of Physiology and Biochemistry, University of California, SanFrancisco, California, 94143, USA

    Leslie C. Timpe, Thomas L. Schwarz, Bruce L. Tempel, Diane M. Papazian, Yuh Nung Jan & Lily Y. Jan

Authors
  1. Leslie C. Timpe
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  2. Thomas L. Schwarz
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  3. Bruce L. Tempel
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  4. Diane M. Papazian
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  5. Yuh Nung Jan
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  6. Lily Y. Jan
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Timpe, L., Schwarz, T., Tempel, B. et al. Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes. Nature 331, 143–145 (1988). https://doi.org/10.1038/331143a0

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