Elsevier

Vision Research

Volume 44, Issue 28, December 2004, Pages 3411-3418
Vision Research

Characterization of mouse cortical spatial vision

https://doi.org/10.1016/j.visres.2004.09.001Get rights and content
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Abstract

Little is known about the spatial vision of mice or of the role the visual cortex plays in mouse visual perception. In order to provide baseline information upon which to evaluate the spatial vision of experimentally and genetically altered mice, we used the visual water task to assess the contrast sensitivity and grating acuity of normal C57BL/6 mice. We then ablated striate cortex (V1) bilaterally and re-measured the same visual functions. Intact mice displayed an inverse “U”-shaped contrast sensitivity curve with a maximum sensitivity near 0.2 cycles/degree (c/d). Grating acuity, measured either by discriminating a sine-wave grating from an equiluminant gray, or vertical from horizontal sine wave gratings, was near 0.55 c/d. Grating acuity and contrast sensitivity were reduced significantly following aspiration of V1. The mouse visual system exhibits fundamental mammalian characteristics, including the feature that striate cortex is involved in processing visual information with the highest sensitivity and spatial frequency.

Keywords

Visual cortex
Visual water task
Acuity
Contrast sensitivity
C57
Mus musculus
V1
Striate
Behavior

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