Associate editor: P. HolzerThe Poly(I:C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery
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Keywords
Maternal immune activation
Depression
Schizophrenia
Animal model
Polyinosinic:polycytidylic acid (Poly(I:C))
Abbreviations
ASD
autism spectrum disorders
DISC1
disrupted in Schizophrenia 1 gene
dsRNA
double-stranded RNA
LPS
lipopolysaccharide
MDD
major depressive disorder
MIA
maternal immune activation
NMDA
N-methyl-d-aspartate
Poly(I:C)
polyinosinic:polycytidylic acid
SSRI/SNRI
selective serotonin or norepinephrine reuptake inhibitor
TLR
toll-like receptor
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These authors have equally contributed to the present article.
Copyright © 2015 The Authors. Published by Elsevier Inc.