Neuron
Volume 70, Issue 5, 9 June 2011, Pages 951-965
ArticleVEGF Signaling through Neuropilin 1 Guides Commissural Axon Crossing at the Optic Chiasm
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open access
Highlights
► NRP1 is expressed by contralateral mouse retinal ganglion cell axons ► NRP1 promotes commissural axon crossing at the optic chiasm as a VEGF164 receptor ► VEGF164 acts directly on retinal growth cones as an attractive guidance signal ► VEGF164 and NRP1 are essential for normal contralateral axon growth in vivo
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Present address: Centre for Cancer Biology, Department of Human Immunology, SA Pathology, Adelaide, SA 5000, Australia
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Present address: UCL Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK
Copyright © 2011 Elsevier Inc.