Brain volume alteration and the correlations with the clinical characteristics in drug-naïve first-episode MDD patients: A voxel-based morphometry study
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Acknowledgments
This work is supported by grants from the National Natural Science Foundation of China (30530250 and 30500150), Science and Technology Foundation of Yunnan Province (2006PT08), 973 Program from the Ministry of Science and Technology of China (2006CB500808, 2009CB941300, 2007CB512303 and 2009CB522006), United Funding of Yunnan Provincial Science and Technology Department and Kunming Medical College (2008C0005R), and Funding of Health Science and Technology Plan of Yunnan Province (2009NS092).
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2023, Journal of Affective DisordersLateralized grey matter volume changes in adolescents versus adults with major depression: SDM-PSI meta-analysis
2023, Psychiatry Research - NeuroimagingAbnormal cortical-striatal-thalamic-cortical circuit centered on the thalamus in MDD patients with somatic symptoms: Evidence from the REST-meta-MDD project
2023, Journal of Affective DisordersCitation Excerpt :In addition to subcortical regions such as thalamus and striatum, our study found that there were significant differences in GMV and GMD among MDD patients with and without somatic symptoms as well as HCs in most cerebral cortical regions including the frontal, occipital, temporal, and insular lobes. This result is consistent with the previous findings that MDD patients have many cortical structural abnormalities (Cheng et al., 2010; Lai and Wu, 2015; Hellewell et al., 2019). Previous studies on somatic symptoms have also uncovered substantial evidence that the activities of the cerebral cortex are related to both somatic symptoms and somatic feelings in MDD patients (Avery et al., 2014; Heinzel et al., 2009; Liu et al., 2021a; Geng et al., 2019).
Preschool Depression and Hippocampal Volume: The Moderating Role of Family Income
2022, Journal of the American Academy of Child and Adolescent PsychiatryPrecuneus connectivity and symptom severity in chronic depression<sup>✰</sup>
2022, Psychiatry Research - NeuroimagingCitation Excerpt :Changes in pre-SMA have been found in several studies on depression: The volume of the right pre-SMA as well as the implicit learning performance was reduced in patients with depression with melancholic features (Exner et al., 2009). In a sample of drug-naïve patients in their first depressive episode, the pre-SMA was the only region with reduced gray matter volume in patients compared to healthy control participants (Cheng et al., 2010). Malejko et al. (2021) found increased error-related neural activity in the dorsal anterior cingulate cortex and pre-SMA in female patients with depression compared to healthy controls in a go/no-go task.
An aberrant hippocampal subregional network, rather than structure, characterizes major depressive disorder
2022, Journal of Affective Disorders
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These authors contributed equally to this article.