ReviewExperimental Models for Studying Food Allergy
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open access
Keywords
Murine Models of Food Allergy
Epictutaneous Sensitization
Spontaneous Sensitization
Humanized Model
FCERIA
IgE
Anaphylaxis
Allergen Sensitization
Allergen Challenge
Abbreviations used in this paper
EPIT
epicutaneous immunotherapy
FCER1A
high-affinity immunoglobulin epsilon receptor subunit alpha
FcεRI
high-affinity immunoglobulin E receptor
GM-CSF
granulocyte-macrophage colony-stimulating factor
HSC
hematopoietic stem cell
Ig
immunoglobulin
IL
interleukin
LCT
long chain triglycerides
MCPT
mouse mast cell protease
MCT
medium chain triglycerides
OIT
oral immunotherapy
PBMC
peripheral blood mononuclear cell
Th
T helper
Treg
regulatory T cell
TSLP
thymic stromal lymphopoietin
WASP
Wiskott–Aldrich syndrome protein
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Author contributions All authors were involved in the conception, writing, and editing of the manuscript.
Conflicts of interest The authors disclose no conflicts.
Funding The research group is supported by a Bridge Grant from the Research Council of Boston Children’s Hospital, an Emerging Investigator Award from FARE, a Senior Research Award from the Crohn’s and Colitis Foundation, and an unrestricted gift from the Mead Johnson Nutrition Company (all to E.F.). C.K. is supported by a postdoctoral training award from the Fonds de recherche Québec Santé (FRQS).
© 2018 The Authors. Published by Elsevier Inc. on behalf of the AGA Institute.