In vivo neuronal firing patterns during human epileptiform discharges replicated by electrical stimulation
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Highlights
► The neuronal firing patterns during interictal epileptiform discharges (IEDs) and after single pulse electrical stimulation (SPES) can be described as burst-only, suppression-only, burst–suppression or no-change. ► Similar neuronal firing patterns can be observed during IEDs and after SPES. ► IEDs and responses to SPES appear to activate similar and generic cortical mechanisms, which may explain transient cognitive impairment.
Abbreviations
IEDs
interictal epileptiform discharges
EEG
electroencephalogram
SPES
single pulse electrical stimulation
Keywords
Extracellular recording
Single unit activity
Epileptiform discharge
Single pulse electrical stimulation
SPES
Epilepsy
Pathophysiology
Human
In vivo
Cited by (0)
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Gonzalo Alarcon and Juan Martinez are joint first authors.
Copyright © 2012 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd.