Prefrontal and auditory tRNS in sequence for treating chronic tinnitus: a modified multisite protocol
Section snippets
Acknowledgments
This study is a part of a randomized clinical trial registered at Iranian Registry of Clinical Trials (Identifier:20586-30/6/2017) and is part of a Ph.D. dissertation project in audiology approved and funded by Iran University of Medical Sciences (944,110,D,94), The International Campus.
Conflicts of interest
The authors declare that there is no conflict of interests.
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Cited by (9)
Using noise for the better: The effects of transcranial random noise stimulation on the brain and behavior
2022, Neuroscience and Biobehavioral ReviewsCitation Excerpt :In that study, the authors found a steeper learning rate than a sham stimulation control condition. tRNS has also been successfully used in the treatment of tinnitus targeting the auditory and prefrontal cortex, with effectiveness depending on the stimulation frequency (Joos et al., 2015; Kreuzer et al., 2019, 2017; Mohsen et al., 2019, 2018; To et al., 2017; Vanneste et al., 2013), chronic pain (Alm and Dreimanis, 2013; Curatolo et al., 2017; Palm et al., 2016), fatigue in multiple sclerosis (MS) (Salemi et al., 2019), improvement in visual perception in migraine (O’Hare et al., 2021) and in attention-deficit/hyperactivity disorder (Berger et al., 2021). The studies reviewed above show promise for the use of tRNS in treating a range of clinical conditions.
Multisite transcranial Random Noise Stimulation (tRNS) modulates the distress network activity and oscillatory powers in subjects with chronic tinnitus
2019, Journal of Clinical NeuroscienceCitation Excerpt :The multisite protocol was more effective in reducing the loudness and annoyance of tinnitus in comparison with the auditory cortex tRNS, while the sham stimulation session had no effects. The amount of tinnitus loudness suppression measured by the visual analog scale was (23.29%, 18.68%) for the multisite and AC-tRNS groups, respectively, and the amount of tinnitus annoyance suppression was (27.63%, 9.4%) respectively; for more detailed subjective results, we refer to Mohsen et al., 2018 [34]. For each frequency band, two repeated-measures ANOVAs were conducted for comparing the absolute and relative power.
The efficacy and safety of multiple sessions of multisite transcranial random noise stimulation in treating chronic tinnitus
2019, Brazilian Journal of OtorhinolaryngologyCitation Excerpt :The proposed mechanism of such findings based on the role of modulating the distress network through modulating the altered function of the dorsolateral prefrontal cortex.35–37 Some cautions should be taken here because we did not use the sham stimulation as a placebo in this study, albeit, it was used in our previous study for single session tRNS and the result showed no placebo effects of tRNS.38 On the other hand, THI is the most clinically used questionnaire for tinnitus, in which we can explore the impact of tinnitus on the patient's functions and daily life.39
Transcranial direct current stimulation for the treatment of tinnitus
2021, Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management: Second Edition