Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1812, Issue 3, March 2011, Pages 381-389
ReviewBehavioural assessments of neurotoxic effects and neurodegeneration in zebrafish☆
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Research Highlights
►Neurotoxicity and neurodegeneration typically have associated behavioural phenotypes. ►Zebrafish behavioural assays have tight parallel with mammalian assays. ►Behavioural assays can test motor and sensory neuron function, and cognitive performance. ►Numerous behavioural assays can be conducted on zebrafish 4 days post fertilization
Abbreviations
AChE
acetylcholinesterase
Anti-AChE
anticholinesterase
CPP
conditioned place preference
CS
conditioned stimulus
dpf
days post fertilization
OKR
optokinetic response
OMR
optomotor response
OP
organophosphorus agent
OSN
olfactory sensory neuron
PEA
phenylethyl alcohol
PTZ
pentylenetetrazole
UCS
unconditioned stimulus
Keywords
Zebrafish
Behaviour
Activity
Sensorimotor
Learning endpoints
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This article is part of a Special Issue entitled Zebrafish Models of Neurological Diseases.
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