Neuron
Volume 35, Issue 6, 12 September 2002, Pages 1015-1017
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Activity-Dependent Synaptogenesis in the Adult Mammalian Cortex

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Abstract

Recent electron microscopic studies provide evidence that the adult cortex generates new synapses in response to sensory activity and that these structural changes can occur rapidly, within 24 hr of sensory stimulation. Together with progress imaging synapses in vivo, the stage appears set for advances in understanding the dynamics and mechanisms of experience-dependent synaptogenesis.

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